Ignite Creation Date:
2024-05-05 @ 4:50 PM
Last Modification Date:
2024-10-26 @ 9:25 AM
Study NCT ID:
NCT00329433
Status:
COMPLETED
Last Update Posted:
2019-03-05
First Post:
2006-05-22
Brief Title:
Study Comparing Desirudin With Heparin to Prevent Vein Clots After Heart and Lung Surgery
Sponsor:
Washington University School of Medicine
Organization:
Washington University School of Medicine
Study Overview
Official Title:
The Use of Desirudin Versus Heparin for Thrombosis Prophylaxis in Cardiothoracic Surgery Patients
Status:
COMPLETED
Status Verified Date:
2011-06
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
A blood clot in the veins also known as deep venous thrombosis DVT is one of the most common complications after surgery This may result in death if a clot breaks off and travel to the lungs this is referred to as pulmonary embolism PE After heart surgery the incidence of DVT ranges from 20-48 and following lung surgery the incidence is 19-26 In order to decrease the likelihood of this complication patients receive by injection a blood thinning medicine Heparin is the usual medicine used for this purpose following heart and lung surgery Recently there have been reports that other medicines may be more effective than heparin for this purpose Also there have been reports that some patients develop antibodies to heparin When this occurs this may prevent the heparin from being effective and may even promote the formation of blood clots Antibodies to heparin may be present more often following heart and lung surgery than other types of surgery There is a new medicine called desirudin Iprivask which may be used instead of heparin to prevent blood clots following heart and lung surgery Desirudin is currently approved by the FDA to prevent blood clots following hip surgery The purpose of this study is to compare desirudin with heparin for the prevention of vein clots after heart and lung surgery
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None