Ignite Creation Date:
2024-05-06 @ 12:16 PM
Last Modification Date:
2024-10-26 @ 12:56 PM
Study NCT ID:
NCT03712020
Status:
COMPLETED
Last Update Posted:
2020-06-24
First Post:
2016-05-31
Brief Title:
Investigating the Role of Active Versus Chronic Coronary Artery Calcification on Acute Myocardial Infarct
Sponsor:
National Heart Centre Singapore
Organization:
National Heart Centre Singapore
Study Overview
Official Title:
Investigating the Role of Active Versus Chronic Coronary Artery Calcification on Acute Myocardial Infarct A Novel Pilot Study Using Sodium-Fluoride Positron Emission Tomography PET and Computed Tomography CT Techniques
Status:
COMPLETED
Status Verified Date:
2020-06
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
Active-AMI
Brief Summary:
The investigator aims to determine the feasibility of understanding the process of active versus chronic calcification using Na-F PET scan and contrast CT scan of the heart
The patient cohort will consist of patients diagnosed to have either acute coronary syndrome ACS comprising of either unstable angina pectoris or acute myocardial infarction or suspected coronary artery disease CAD The PET images will be compared to images obtained from standard contrast CT of the coronaries This study will provide additional insights about active versus non-active calcification amongst patients with ACS or suspected CAD
The patient cohort will consist of patients diagnosed to have either acute coronary syndrome ACS comprising of either unstable angina pectoris or acute myocardial infarction or suspected coronary artery disease CAD The PET images will be compared to images obtained from standard contrast CT of the coronaries This study will provide additional insights about active versus non-active calcification amongst patients with ACS or suspected CAD
Detailed Description:
Contemporary techniques used to visualize coronary artery calcification include standard non-contrast computed tomography CT of the coronaries measuring amount of calcium deposition in the coronaries contrast CT and more recently using sodium-fluoride Na-F positron emission tomography PET to image coronary and valvular calcification Na-F has been shown to accumulate in areas of active calcification where contrast CT of the heart has been shown to accumulate in areas of chronic calcification The investigator aims to determine the feasibility of understanding the process of active versus chronic calcification using Na-F PET scan and contrast CT scan of the heart
The patient cohort will consist of patients diagnosed to have either acute coronary syndrome ACS comprising of either unstable angina pectoris or acute myocardial infarction or suspected coronary artery disease CAD The PET images will be compared to images obtained from standard contrast CT of the coronaries This study will provide additional insights about active versus non-active calcification amongst patients with ACS or suspected CAD
The patient cohort will consist of patients diagnosed to have either acute coronary syndrome ACS comprising of either unstable angina pectoris or acute myocardial infarction or suspected coronary artery disease CAD The PET images will be compared to images obtained from standard contrast CT of the coronaries This study will provide additional insights about active versus non-active calcification amongst patients with ACS or suspected CAD
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None