Ignite Creation Date:
2024-05-05 @ 4:49 PM
Last Modification Date:
2024-10-26 @ 9:25 AM
Study NCT ID:
NCT00328991
Status:
COMPLETED
Last Update Posted:
2006-05-24
First Post:
2006-05-22
Brief Title:
Clinical Trial Evaluating Efficacy of Duct Tape for Treatment of Warts
Sponsor:
Minneapolis Veterans Affairs Medical Center
Organization:
Minneapolis Veterans Affairs Medical Center
Study Overview
Official Title:
Double-Blind Randomized Control Trial To Evaluate the Efficacy of Duct Tape Versus Placebo for the Treatment of Verruca Vulgaris
Status:
COMPLETED
Status Verified Date:
2006-01
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
This study is a double-blinded controlled clinical intervention trial to evaluate the efficacy of duct tape occlusions therapy for the treatment of common warts 80 patients completed this study and were randomized 11 to receive pads which contained either moleskintransparent duct tape or moleskin alone The patients wore the pad over the target wart for 7 days at a time removed the pad on the evening of the 7th day and replaced the pad on the 8th day This cycle was repeated for 8 weeks or until the wart resolved The hypothesis was that duct tape occlusion therapy would be more therapeutic than moleskin for the treatment of the common wart However in our study there was only 21 resolution rate in the duct tape arm vs 22 in the control group
Detailed Description:
ABSTRACT 233 word count
Objective To evaluate the efficacy of duct tape occlusion therapy for the treatment of common warts
Design A double-blinded controlled clinical intervention trial Setting Veterans Affairs Medical Center Participants A total of 90 immunocompetent adult volunteers with at least one wart measuring between 2-15 mm were enrolled in this study between October 2004 and July 2005 80 patients completed the study
Intervention Patients were randomized using a computer-generated code to receive either pads consisting of moleskin with transparent duct tape active or moleskin alone control Patients were instructed to wear the pads for 7 consecutive days and leave the pad off on the 7th evening This process was repeated for 2 months or until the wart resolved whichever occurred first Follow-up visits occurred at 1 and 2 months
Main Outcome Measure 100 resolution of the wart Secondary outcomes included change in size of the target wart and recurrence rates at 6 months for warts with complete resolution
Results There were no statistically significant differences in the proportions of patients with resolution of the target wart duct tape839 21 vs control941 22 Of patients with complete resolution 75 68 in the duct tape group and 33 39 of those in the control group had recurrence of the target wart by the sixth month
Conclusions Occlusive therapy with transparent duct tape is not significantly better than moleskin alone for treatment of common warts in adults
Objective To evaluate the efficacy of duct tape occlusion therapy for the treatment of common warts
Design A double-blinded controlled clinical intervention trial Setting Veterans Affairs Medical Center Participants A total of 90 immunocompetent adult volunteers with at least one wart measuring between 2-15 mm were enrolled in this study between October 2004 and July 2005 80 patients completed the study
Intervention Patients were randomized using a computer-generated code to receive either pads consisting of moleskin with transparent duct tape active or moleskin alone control Patients were instructed to wear the pads for 7 consecutive days and leave the pad off on the 7th evening This process was repeated for 2 months or until the wart resolved whichever occurred first Follow-up visits occurred at 1 and 2 months
Main Outcome Measure 100 resolution of the wart Secondary outcomes included change in size of the target wart and recurrence rates at 6 months for warts with complete resolution
Results There were no statistically significant differences in the proportions of patients with resolution of the target wart duct tape839 21 vs control941 22 Of patients with complete resolution 75 68 in the duct tape group and 33 39 of those in the control group had recurrence of the target wart by the sixth month
Conclusions Occlusive therapy with transparent duct tape is not significantly better than moleskin alone for treatment of common warts in adults
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None