Ignite Creation Date:
2024-05-06 @ 12:08 PM
Last Modification Date:
2024-10-26 @ 12:55 PM
Study NCT ID:
NCT03688828
Status:
COMPLETED
Last Update Posted:
2021-10-26
First Post:
2018-09-27
Brief Title:
Evaluation of Saccharomyces Boulardii Combined With Standard Quadruple Therapy for Eradication of Helicobacter Pylori
Sponsor:
Huazhong University of Science and Technology
Organization:
Huazhong University of Science and Technology
Study Overview
Official Title:
The Evaluation of Saccharomyces Boulardii Sachets Combined With Standard Quadruple Therapy for Eradication of Helicobacter Pylori a Prospective Multi-Center Trial
Status:
COMPLETED
Status Verified Date:
2021-10
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The eradication rate of standard quadruple therapy has become less successful due to low compliance and high resistance to the antibiotics Therefore it is necessary to develop new treatment strategies that increase the eradication rate and reduce adverse effects The aims of this prospective study is to investigate the efficacy of Saccharomyces Boulardii sachets for eradication of Hp compared with standard quadruple therap
Detailed Description:
In China the first-line therapy to treat Helicobacter pylori Hp consists of a bismuth-based proton pump inhibitor PPI and two antibiotics for 14 days But eradication has become less successful due to low compliance and high resistance to the antibiotics Therefore it is necessary to develop new treatment strategies that increase the eradication rate and reduce adverse effects Several studies previously suggested that probiotics could be effective for improving Hp eradication rate or reducing adverse events with PPI-based triple therapy But their effect for eradication of Hp is not yet conclusive And the experiments now available about efficacy of Saccharomyces Boulardii were mainly combined with triple therapy The aims of this prospective study is to investigate the efficacy of Saccharomyces Boulardii sachets for eradication of Hp compared with standard quadruple therapy
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None