Ignite Creation Date:
2024-05-06 @ 12:03 PM
Last Modification Date:
2024-10-26 @ 12:53 PM
Study NCT ID:
NCT03667872
Status:
UNKNOWN
Last Update Posted:
2018-12-27
First Post:
2018-09-10
Brief Title:
Efficacy and Safety of DBS in Patients With Treatment-Resistant Depression
Sponsor:
Beijing Pins Medical Co Ltd
Organization:
Beijing Pins Medical Co Ltd
Study Overview
Official Title:
Efficacy and Safety of MRI Compatible and Long-term LFP Recordable Deep Brain Stimulation in Patients With Treatment-Resistant Depression
Status:
UNKNOWN
Status Verified Date:
2018-12
Last Known Status:
NOT_YET_RECRUITING
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The habenula Hb is an ancient structure located at the center of the dorsal diencephalic conduction system a pathway involved in linking forebrain to midbrain regions An increasing number of studies indicated that the lateral habeluna LHb is overactivity during depressive behaviors in rats where it could drive the changes in midbrain monoamine neurotransmitter linked to depression However the efficiency and mechanism of deep brain stimulation DBS of the LHb andor its major afferent bundle ie stria medullaris thalami could treat treatment-resistant major depression TRD is still unclear This research will investigate the effectiveness and mechanism of bilateral MRI Compatible and Long-term LFP Recordable DBS to habenula andor its major afferent bundle for treatment TRD patients
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None