Ignite Creation Date:
2024-05-05 @ 4:48 PM
Last Modification Date:
2024-10-26 @ 9:24 AM
Study NCT ID:
NCT00314340
Status:
COMPLETED
Last Update Posted:
2017-05-30
First Post:
2006-04-11
Brief Title:
A Comparison of the Addiction Liability of Hydrocodone and Sustained Release Morphine
Sponsor:
University of California Davis
Organization:
University of California Davis
Study Overview
Official Title:
A CTSC Clinical Research Center Study A Comparison of the Addiction Liability of Hydrocodone and Sustained Release Morphine
Status:
COMPLETED
Status Verified Date:
2017-05
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Characterize the relative abuse liability of a short versus a long acting opioid in chronic pain patients
Detailed Description:
A placebo-controlled double-blind crossover trial will be conducted providing study subjects either hydrocodoneacetaminophen 30mg975mg sustained release morphine 45mg or placebo on separate GCRC visits A long acting comparator slow-release morphine sulfate 45 mg will be chosen because of its putative equianalgesic effects to the dose of hydrocodone 30 mg selected Subjects will participate in the three sessions at the UC DavisMather Medical Center General Clinical Research Center GCRC at intervals of 7-10 days Sessions will be approximately 360 min in duration Subjects will receive either hydrocodoneacetaminophen or sustained release morphine around-the-clock for 7-10 days prior to the experimental session At each experimental session an assessment of abuse liability will be completed before the intake of medications as well as at 0 60 120 180 240 minutes after the ingestion of the study medication
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None