Ignite Creation Date:
2024-05-06 @ 11:59 AM
Last Modification Date:
2024-10-26 @ 12:52 PM
Study NCT ID:
NCT03647787
Status:
COMPLETED
Last Update Posted:
2019-09-19
First Post:
2018-08-22
Brief Title:
White Matter Integrity According to BDNF Genotype After Stroke
Sponsor:
Samsung Medical Center
Organization:
Samsung Medical Center
Study Overview
Official Title:
Changes of White Matter Integrity According to BDNF Genotype During Motor Recovery After Stroke
Status:
COMPLETED
Status Verified Date:
2018-09
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The aim of this study was to investigate differential plastic changes of fractional anisotropy FA in the corticospinal tract CST the intrahemispheric corticocortical tract from the primary motor cortex to ventral premotor cortex M1PMv and the corpus callosum CC from 2 weeks to 3 months after stroke according to BDNF genotype
Detailed Description:
The aims of this study were to investigate plastic changes in the fractional anisotropy FA of three motor-related white matter fibers according to the BDNF genotype from 2 weeks to 3 months after stroke onset one is a the majority of fibers from M1 to medullary oblongata CST another is the intrahemispheric connection from M1 to ventral premotor cortex M1PMv and the other is the interhemispheric connection between bilateral M1s CC There were also to investigate the relationships between motor impairment and tract-related FA of white matter tracts in each BDNF genotype
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None