Ignite Creation Date:
2024-05-06 @ 11:46 AM
Last Modification Date:
2024-10-26 @ 12:50 PM
Study NCT ID:
NCT03599206
Status:
COMPLETED
Last Update Posted:
2024-02-12
First Post:
2018-07-03
Brief Title:
ONES Grant CXCL10CXCR3 Regulation of Ozone-Induced Epithelial Permeability
Sponsor:
Robert Tighe MD
Organization:
Duke University
Study Overview
Official Title:
CXCL10CXCR3 Regulation of Ozone-Induced Epithelial Permeability
Status:
COMPLETED
Status Verified Date:
2024-02
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The purpose of this research study to understand how environmental and genetic factors may be involved in lung function Study participants will undergo a 1-day screening that includes a blood draw and breathing testing return for a two-day series of testing to include blood draw and brief breathing test before and after an inhaled challenge with either filtered air FA or ozone O3 Participants return the next day for a brief breathing test a blood draw and a procedure called bronchoscopy to evaluate the lung after the challenge Participants then return 18 - 20 days later to repeat the two-day series of testing to be challenged with the exposure not received on the first series FA or O3 Each visit will take about 3 - 35 hours Follow-up phone calls from the study team will occur at 24 hours after each 2-day test series Total study duration is about one to one-and a half months
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
True
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
False
Is an FDA AA801 Violation?:
None