Ignite Creation Date:
2024-05-06 @ 11:43 AM
Last Modification Date:
2024-10-26 @ 12:49 PM
Study NCT ID:
NCT03581812
Status:
COMPLETED
Last Update Posted:
2020-02-05
First Post:
2018-06-23
Brief Title:
Snack Foods and Their Impact on Gastrointestinal Microbiology Function and Symptoms
Sponsor:
Kings College London
Organization:
Kings College London
Study Overview
Official Title:
Snack Foods and Their Impact on Gastrointestinal Physiology Luminal Microbiology and Gastrointestinal Symptoms
Status:
COMPLETED
Status Verified Date:
2020-02
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
OptiGut
Brief Summary:
The purpose of this study is to evaluate the impact of replacing usual snacks with alternative snack foods on gut health in a population of habitual snackers with low fibre intake
Detailed Description:
Diet is a crucial target for the improvement of human health In the modern world diets are diverse and diet related diseases are becoming more and more common In particular it is becoming increasingly apparent that the bacteria that live in the gut are strongly linked to both diet and health Bacteria in the gut can be beneficial or harmful and the health of the gut relies on the beneficial bacteria outnumbering the harmful ones Diet has a great impact on the bacterial composition of the gut In turn the gut bacteria play diverse roles in human health influencing not only the gut but also the health of the immune system heart and brain Therefore optimising the composition of the gut bacterial is vital to human health and wellbeing
It has been shown that snacks between meals contributes 420 - 480 calories per day almost a quarter of the recommended intake Therefore snack choices are an area of diet and lifestyle that have the potential to influence diet and in turn the health of our gut and gut bacteria We would like to assess the effect of replacing usual snacks with alternative snack foods that we believe have benefits for gut health
The primary aim of the study is to investigate whether the replacement of usual snacks has an effect on gut bacterial composition specifically the abundance of Bifidobacteria Secondary aims include the effect of the intervention snacks on additional measures of gut health such as gut transit time the frequency and consistency of bowel movements and gut symptoms eg heartburn nausea belching etc The effect of snack foods on metabolites in the blood eg glucose insulin lipids will also be determined Finally the impact of snack replacement on mood and quality of life will be assessed
It has been shown that snacks between meals contributes 420 - 480 calories per day almost a quarter of the recommended intake Therefore snack choices are an area of diet and lifestyle that have the potential to influence diet and in turn the health of our gut and gut bacteria We would like to assess the effect of replacing usual snacks with alternative snack foods that we believe have benefits for gut health
The primary aim of the study is to investigate whether the replacement of usual snacks has an effect on gut bacterial composition specifically the abundance of Bifidobacteria Secondary aims include the effect of the intervention snacks on additional measures of gut health such as gut transit time the frequency and consistency of bowel movements and gut symptoms eg heartburn nausea belching etc The effect of snack foods on metabolites in the blood eg glucose insulin lipids will also be determined Finally the impact of snack replacement on mood and quality of life will be assessed
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None