Ignite Creation Date:
2024-05-05 @ 4:45 PM
Last Modification Date:
2024-10-26 @ 9:23 AM
Study NCT ID:
NCT00302289
Status:
COMPLETED
Last Update Posted:
2006-03-14
First Post:
2006-03-13
Brief Title:
B181 Stimulation of Thermogenesis by Bio-Active Food Ingredients
Sponsor:
University of Copenhagen
Organization:
University of Copenhagen
Study Overview
Official Title:
B181 Stimulation of Thermogenesis by Bio-Active Food Ingredients
Status:
COMPLETED
Status Verified Date:
2000-12
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The primary aim was to measure the effect of green tea extract tyrosine and caffeine on energy expenditure appetite ratings and spontaneous energy intake together with recording of side effects in healthy normal weight subjects
Detailed Description:
Background Long-term weight maintenance of a weight loss is often unsuccessful Often a weight regain is observed in most studies that could indicate that most subjects are not able to change their eating habits There is a need for simple and safe methods to prevent weight gain and re-gain ie by increasing thermogenesis and decrease spontaneous energy intake EI Studies have shown that nutritional and food-related non-nutritional factors influence the adjustment of EI and EE as the compounds can enhance the diet-induced thermogenesis DIT and suppress appetite
Method The present study was designed as a 4-way crossover randomised placebo controlled dou-ble-blind study Each treatment was separated by 3 d washout period All treatments were administered as tablets containing either 500 mg green tea extract whereof 125 mg cate-chins 400 mg tyrosine 50 mg anhydrous caffeine or placebo
on each test day body weight and composition was assessed All participants underwent a 45-h assessment of energy expenditure by indirect calorimetry in a ventilated hood Energy intake recorded of an ad libitum pasta salad brunch served after the last hood measurement
Subjects Twelve healthy lean 20BMI25 weight stable non-smoking subjects between 18-40 years of age were tested 4 times each with a wash-out period of at least 3 days
Method The present study was designed as a 4-way crossover randomised placebo controlled dou-ble-blind study Each treatment was separated by 3 d washout period All treatments were administered as tablets containing either 500 mg green tea extract whereof 125 mg cate-chins 400 mg tyrosine 50 mg anhydrous caffeine or placebo
on each test day body weight and composition was assessed All participants underwent a 45-h assessment of energy expenditure by indirect calorimetry in a ventilated hood Energy intake recorded of an ad libitum pasta salad brunch served after the last hood measurement
Subjects Twelve healthy lean 20BMI25 weight stable non-smoking subjects between 18-40 years of age were tested 4 times each with a wash-out period of at least 3 days
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None