Ignite Creation Date:
2024-05-06 @ 11:36 AM
Last Modification Date:
2024-10-26 @ 12:47 PM
Study NCT ID:
NCT03556176
Status:
COMPLETED
Last Update Posted:
2020-05-18
First Post:
2018-05-08
Brief Title:
The Influence of 5-HTTLPR and BDNF Polymorphisms on Anxiety and Mood After Acute Exercise
Sponsor:
Universidade Federal de Goias
Organization:
Universidade Federal de Goias
Study Overview
Official Title:
The Influence of 5-HTTLPR and BDNF Polymorphisms on Anxiety and Mood After Acute Exercise
Status:
COMPLETED
Status Verified Date:
2020-05
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The Influence of 5-HTTLPR and BDNF Polymorphisms on Anxiety and Mood After Acute Exercise
Introduction The 5-HTTLPR SLC6A4 and BDNF Val66Met polymorphism presents an action on the modulation of human behavior and has received great attention as a risk factor for several psychiatric disorders In recent years a growing number of studies have evaluated the association between these polymorphisms and personality traits related to anxiety and depression Objectives To determine the frequencies of 5-HTTLPR and BDNF polymorphisms in a college students population To determine the influence of 5-HTTLPR and BDNF polymorphisms on mood states and anxiety after acute physical exercise Material and Methods Four hundred 400 College students will be assessed
In the first phase of the study the following procedures will be performed Screening Aerobic Fitness Assessment Step Test Questionnaires PAR-Q Habitual Physical Activity Level Beck Anxiety and Depression Scale State-Trait Anxiety and Perceived Stress Scale blood sample collection and genotyping In the second phase of the study two 2 groups with or without polymorphisms will be selected for each gene These groups will be submitted to four conditions three experimental conditions and one control condition carried out randomly and separated by an interval of 1 week In the experimental Conditions the volunteers will perform treadmill exercises sessions 30 minutes in three different intensities light moderate and vigorous and will respond to the Borg Scale at 10 20 e 30 minutes In the control condition the volunteers will be instructed to remain seated quiet rest relaxed and silent for 30 minutes In both conditions the volunteers will complete the Profile of Mood States POMS and State-Anxiety STAY 05 five minutes before and 5 five and 20 twenty minutes following the interventions
Introduction The 5-HTTLPR SLC6A4 and BDNF Val66Met polymorphism presents an action on the modulation of human behavior and has received great attention as a risk factor for several psychiatric disorders In recent years a growing number of studies have evaluated the association between these polymorphisms and personality traits related to anxiety and depression Objectives To determine the frequencies of 5-HTTLPR and BDNF polymorphisms in a college students population To determine the influence of 5-HTTLPR and BDNF polymorphisms on mood states and anxiety after acute physical exercise Material and Methods Four hundred 400 College students will be assessed
In the first phase of the study the following procedures will be performed Screening Aerobic Fitness Assessment Step Test Questionnaires PAR-Q Habitual Physical Activity Level Beck Anxiety and Depression Scale State-Trait Anxiety and Perceived Stress Scale blood sample collection and genotyping In the second phase of the study two 2 groups with or without polymorphisms will be selected for each gene These groups will be submitted to four conditions three experimental conditions and one control condition carried out randomly and separated by an interval of 1 week In the experimental Conditions the volunteers will perform treadmill exercises sessions 30 minutes in three different intensities light moderate and vigorous and will respond to the Borg Scale at 10 20 e 30 minutes In the control condition the volunteers will be instructed to remain seated quiet rest relaxed and silent for 30 minutes In both conditions the volunteers will complete the Profile of Mood States POMS and State-Anxiety STAY 05 five minutes before and 5 five and 20 twenty minutes following the interventions
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None