Ignite Creation Date:
2024-05-05 @ 4:45 PM
Last Modification Date:
2024-10-26 @ 9:23 AM
Study NCT ID:
NCT00301314
Status:
COMPLETED
Last Update Posted:
2010-01-12
First Post:
2006-03-09
Brief Title:
A Retrospective Study of Toxicity and Outcome of High Dose Chemotherapy With Autologous Stem Cell Transplant in Patients With Hodgkin Lymphoma HL
Sponsor:
Royal Marsden NHS Foundation Trust
Organization:
Royal Marsden NHS Foundation Trust
Study Overview
Official Title:
None
Status:
COMPLETED
Status Verified Date:
2010-01
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The majority of patients with Hodgkin Lymphoma HLare cured with radiation therapy andor combination chemotherapy However patients who relapse after attaining a complete remission with chemotherapy and those with primary refractory disease have a poor outcome with conventional chemotherapy regimens Treatment results with standard-dose second-line regimens produce low complete remission rates and minimal survival benefit Single institution studies have shown better outcome after autologous stem cell transplant in this group of patients when compared to historical controls receiving conventional treatment In this retrospective review we aim to analyze outcome and determine independent prognostic factors which would correlate with the long-term outcome of patients with HL who received an autologous stem cell transplant in the past at the Royal Marsden Hospital Eligible patients those on current-follow-up identified from the transplant database will be eligible for the study
Accrual of eligible patients currently under follow-up will be performed in clinic at the time of next appointment All patients accrued will give informed consent to participate in the study for retrospective case note review after discussion with a study investigator and after receiving a study information sheet The results of the analysis will be published in a peer-reviewed medical journal
Accrual of eligible patients currently under follow-up will be performed in clinic at the time of next appointment All patients accrued will give informed consent to participate in the study for retrospective case note review after discussion with a study investigator and after receiving a study information sheet The results of the analysis will be published in a peer-reviewed medical journal
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None