Ignite Creation Date:
2024-05-06 @ 11:30 AM
Last Modification Date:
2024-10-26 @ 12:46 PM
Study NCT ID:
NCT03537586
Status:
RECRUITING
Last Update Posted:
2024-01-11
First Post:
2018-05-15
Brief Title:
A Single Center Diagnostic Cross-sectional Study of Coronary Microvascular Dysfunction
Sponsor:
NYU Langone Health
Organization:
NYU Langone Health
Study Overview
Official Title:
A Single Center Diagnostic Cross-sectional Study of Coronary Microvascular Dysfunction
Status:
RECRUITING
Status Verified Date:
2024-01
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Among patients with stable ischemic heart disease who are referred for coronary angiography a substantial proportion have non-obstructive coronary artery disease CAD Ischemia based on symptoms or stress testing may be due to coronary microvascular dysfunction in up to 40 of these patients However the mechanisms and optimal treatment of coronary microvascular dysfunction are unknown Aberrant platelet activity and inflammation have been hypothesized as mechanisms of microvascular dysfunction Investigators plan to evaluate association between platelet activity inflammation and coronary microvascular dysfunction in stable women referred for coronary angiography and to identify non-invasive correlates of coronary microvascular dysfunction in these patients
Detailed Description:
The objectives of this study are to
1 Investigate platelet activity and inflammation in patients with and without coronary microvascular disease who are referred for coronary angiography for the evaluation of stable ischemic heart disease and are found to have non-obstructuve epicardial CAD
2 To identify correlates of coronary microvascular dysfunction in non coronary microvascular beds that can be characterized in vivo
1 Investigate platelet activity and inflammation in patients with and without coronary microvascular disease who are referred for coronary angiography for the evaluation of stable ischemic heart disease and are found to have non-obstructuve epicardial CAD
2 To identify correlates of coronary microvascular dysfunction in non coronary microvascular beds that can be characterized in vivo
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
False
Is an FDA AA801 Violation?:
None