Ignite Creation Date:
2024-05-06 @ 11:28 AM
Last Modification Date:
2024-10-26 @ 12:45 PM
Study NCT ID:
NCT03522220
Status:
UNKNOWN
Last Update Posted:
2018-06-06
First Post:
2018-04-30
Brief Title:
Augmentation of Neuronal Network Plasticity in Schizophrenia
Sponsor:
Universitätsklinikum Hamburg-Eppendorf
Organization:
Universitätsklinikum Hamburg-Eppendorf
Study Overview
Official Title:
Augmentation of Neuronal Network Plasticity in Schizophrenia
Status:
UNKNOWN
Status Verified Date:
2018-06
Last Known Status:
RECRUITING
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
SCZ
Brief Summary:
Current pathophysiological models of schizophrenia focus on disconnectivity of distributed neuronal systems to explain the multitude of psychic symptoms However therapeutic strategies targeting this specific pathobiology are lacking Our recent work provides strong evidence that complex video-game training interventions facilitate fronto-hippocampal structural and functional connectivity within 2 months in healthy subjects The planned project transfers this knowledge into a training study in schizophrenic patients to counteract disease-related disconnectivity Underlying mechanisms and behavioral effects are extensively parametrized by resting state functional magnetic resonance imaging fMRI diffusion tensor imaging DTI spectroscopy and clinical short- and long-term outcome
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None