Ignite Creation Date:
2024-05-06 @ 11:28 AM
Last Modification Date:
2024-10-26 @ 12:45 PM
Study NCT ID:
NCT03527654
Status:
COMPLETED
Last Update Posted:
2022-05-26
First Post:
2018-04-27
Brief Title:
SER Hispano Longitudinal Study
Sponsor:
Duke University
Organization:
Duke University
Study Overview
Official Title:
SER Study Salud Estrés y Resilencia Health Stress and Resilience Among Young Adult Hispanic Immigrants in the US
Status:
COMPLETED
Status Verified Date:
2022-05
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Hispanic immigrants to the US are more likely to experience negative health outcomes the longer they live in the US For example over time Hispanic immigrants engage in riskier behaviors such as substance abuse violence and risky sex and experience more depressive symptoms The stress associated with the acculturation process acculturation stress and resilience at the individual family community and societal levels appear to play important roles in influencing risks However little is known about the causal mechanisms linking acculturation stress resilience and health outcomes among Hispanic immigrants Further little is known about what precise types of stressors eg occupational stress vs discrimination and resilience factors eg individual coping vs family support have the most important influence on health trajectories of Hispanic immigrants The proposed longitudinal study N 385 will investigate the effects of acculturation stress and resilience on co-occurring substance abuse intimate partner violence HIV risk and depression ie syndemic conditions and biological stress among young adult Hispanic immigrants in the US More specifically the proposed project aims to 1 test theoretical links between the cumulative impact of acculturation stress and resilience on syndemic conditions and biological stress among recent young adult Hispanic immigrants over a two-year period and 2 identify the specific types of acculturation stressors and resilience factors at the individual family community and societal levels that are most important in predicting syndemic conditions and biological stress among this population over time Young adult low-income Hispanic immigrant men and women within the first 10 years of immigration will be followed for two years Biopsychosocial data will be collected from participants at baseline and then 6 months FU1 12 months FU2 18 months FU3 and 24 months later FU4 Culturally specific measures of acculturation stress and resilience will be used to assess for individual family community and societal risk and protective factors for syndemic conditions Blood and urine samples will be obtained from participants to measure systemic inflammation IL 6 IL8 and IL 18 and oxidative stress F2 isoprostanes previously validated biomarkers for psychological stress Various descriptive univariate and multivariate statistics including latent growth curve modeling will be used to address aims 1-2 The findings from this study have the potential to identify risk and protective factors for the decay in heath among Hispanic immigrants A precise and culturally informed understanding of these phenomena is foundational for designing interventions that can ultimately promote the health and wellbeing of Hispanic immigrants the largest immigrant group in the US This study also has the potential to lay the theoretical foundation for biopsychosocial health disparities research in other populations
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| 1R01MD012249-01 | NIH | None | httpsreporternihgovquickSearch1R01MD012249-01 |