Ignite Creation Date:
2024-05-06 @ 11:23 AM
Last Modification Date:
2024-10-26 @ 12:44 PM
Study NCT ID:
NCT03501706
Status:
RECRUITING
Last Update Posted:
2024-05-10
First Post:
2018-04-09
Brief Title:
An Assessment of Cognitive Improvement Training Among Mid-life Individuals
Sponsor:
University of Kansas
Organization:
University of Kansas
Study Overview
Official Title:
Remediation of Elevated Delay Discounting in Mid-life Individuals A Stage-II Trial
Status:
RECRUITING
Status Verified Date:
2024-05
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
RehabEF
Brief Summary:
Many health-relevant decisions involve intertemporal now vs later tradeoffs Extensive literature indicates that many negative health and financial consequences suffered in mid-life are linked to adversity and disadvantage during early developmental periods of life Individuals who continue to engage in these types of unhealthy behaviors despite awareness of the health consequences are exhibiting an inability to delay gratification
Delay discounting DD is quantified in human studies by determining the rate at which an individual discounts a delayed reward while executive function EF is defined as the set of cognitive processes that are responsible for helping individuals manage life tasks and achieve goals This research will attempt to reduce DD via EF training in a population of mid-life individuals with risk factors established during early-life disadvantage
Delay discounting DD is quantified in human studies by determining the rate at which an individual discounts a delayed reward while executive function EF is defined as the set of cognitive processes that are responsible for helping individuals manage life tasks and achieve goals This research will attempt to reduce DD via EF training in a population of mid-life individuals with risk factors established during early-life disadvantage
Detailed Description:
Many health-relevant decisions involve intertemporal now vs later tradeoffs where unhealthy choices involve immediate benefits and delayed costs compared to healthy choices with immediate costs and delayed benefits Reinforcement for unhealthy behaviors are immediate while the reinforcement for healthier alternatives are delayed Thus individuals who continue to engage in these types of unhealthy behaviors despite awareness of the health consequences are exhibiting an inability to delay gratification
Delay discounting DD is quantified in human studies by determining the rate at which an individual discounts a delayed reward typically assessed by having subjects choose between a rewards available immediately and a larger reward available following a delay For the purpose of this study the investigators define executive function EF as the set of cognitive processes that are responsible for helping individuals manage life tasks and achieve goals eg planning working memory
The approach of targeting preference for immediate rewards exhibited by elevated DD is highly innovative Multiple studies provide compelling evidence that strengthening EF may decrease DD Extensive literature indicates that many negative health and financial consequences suffered in mid-life are linked to adversity and disadvantage during early developmental periods of life By targeting a mechanism of various negative aging-related outcomes elevated DD the proposed research may have the novel impact on broadly remediating the health and wellness of mid-life individuals at increased risk for poor consequences due to early-life disadvantage
This research will attempt to reduce Delay Discounting via Executive Functioning training in a population of mid-life individuals with risk factors established during early-life disadvantage DD EF and associated health behaviorsoutcomes will be assessed at baseline following training and at 3- and 6-month follow-up Participants will receive Active EF training or Control training Given the established effect of Active training in reducing DD in stimulant-dependent individuals the study team expect reductions in DD improvements in EF and improvements in associated health behaviorsoutcomes following Active training and at follow-up with no improvements in the Control group
Delay discounting DD is quantified in human studies by determining the rate at which an individual discounts a delayed reward typically assessed by having subjects choose between a rewards available immediately and a larger reward available following a delay For the purpose of this study the investigators define executive function EF as the set of cognitive processes that are responsible for helping individuals manage life tasks and achieve goals eg planning working memory
The approach of targeting preference for immediate rewards exhibited by elevated DD is highly innovative Multiple studies provide compelling evidence that strengthening EF may decrease DD Extensive literature indicates that many negative health and financial consequences suffered in mid-life are linked to adversity and disadvantage during early developmental periods of life By targeting a mechanism of various negative aging-related outcomes elevated DD the proposed research may have the novel impact on broadly remediating the health and wellness of mid-life individuals at increased risk for poor consequences due to early-life disadvantage
This research will attempt to reduce Delay Discounting via Executive Functioning training in a population of mid-life individuals with risk factors established during early-life disadvantage DD EF and associated health behaviorsoutcomes will be assessed at baseline following training and at 3- and 6-month follow-up Participants will receive Active EF training or Control training Given the established effect of Active training in reducing DD in stimulant-dependent individuals the study team expect reductions in DD improvements in EF and improvements in associated health behaviorsoutcomes following Active training and at follow-up with no improvements in the Control group
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| 7R01AG048904 | NIH | None | httpsreporternihgovquickSearch7R01AG048904 |