Ignite Creation Date:
2024-05-06 @ 11:17 AM
Last Modification Date:
2024-10-26 @ 12:43 PM
Study NCT ID:
NCT03480737
Status:
UNKNOWN
Last Update Posted:
2019-11-14
First Post:
2018-03-12
Brief Title:
rTMS and EF Training for Working Memory Deficits in Adolescent Psychopathology
Sponsor:
Bradley Hospital
Organization:
Bradley Hospital
Study Overview
Official Title:
rTMS and Executive Functioning Training for Working Memory Deficits in Adolescent Psychopathology
Status:
UNKNOWN
Status Verified Date:
2019-11
Last Known Status:
RECRUITING
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Executive functioning EF deficits are a core transdiagnostic feature of psychopathology and one of the strongest predictors of clinical and functional outcomes yet there remains a dearth of treatments available for EF deficits EF is a collection of cognitive control processes that includes working memory ie maintainmanipulate data not perceptually present inhibition ie inhibitcontrol of attention thoughts behaviors and flexibility ie shift flexibly between taskssets These EF subdomains are subserved by a network ie cognitive control network of frontal eg dorsolateral prefrontal cortex DLPFC parietal and subcortical regions with hypoactivation in such regions often underlying EF deficits There is a recent call in psychiatry to develop experimental therapeutics that target anomalous neural systems underlying symptomology Repetitive transcranial magnetic stimulation rTMS is a therapeutic non-invasive method of cortical excitability modulation High frequency rTMS to the left DPLFC has an activating effect on the cognitive control network with initial research in adults finding a subsequent enhancing effect on working memory inhibition and flexibility rTMS represents a very promising potential tool to target EF deficits in psychopathology
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
True
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
False
Is an FDA AA801 Violation?:
None