Ignite Creation Date:
2024-05-05 @ 4:42 PM
Last Modification Date:
2024-10-26 @ 9:23 AM
Study NCT ID:
NCT00297154
Status:
COMPLETED
Last Update Posted:
2020-03-03
First Post:
2006-02-27
Brief Title:
The Effect of Diet and Exercise in Heart Failure
Sponsor:
Baylor College of Medicine
Organization:
Baylor College of Medicine
Study Overview
Official Title:
Lifestyle Modification in the Treatment of Heart Failure
Status:
COMPLETED
Status Verified Date:
2020-02
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
LIMIT-HF
Brief Summary:
A growing number of people in this country are overweight or obese This is concerning as increasing weight has been shown to increase the risk of developing heart failure However there is also research to suggest that in people who already have heart failure heavier people live longer So how does being overweight put a person at risk for heart failure but once they have heart failure protect them There is no clear explanation for this dilemma
People who are obese commonly have other diseases such as high blood pressure high cholesterol and diabetes that increase the risk of developing heart disease It is this group of diseases that is referred to as The Metabolic Syndrome People with the metabolic syndrome also have increased levels of inflammation and clotting proteins in their blood stream Current treatment of the metabolic syndrome involves using medications for cholesterol blood pressure and diabetes Diet and exercise are also commonly recommended
Lifestyle intervention programs are programs that help people lose weight by changing their eating habits and exercise activity routines Weight loss and exercise have been shown to lower the risk of developing diabetes and improve diabetes control improve cholesterol abnormalities and lower blood pressure These programs have not previously included heart failure patients however
We hypothesize that using a lifestyle intervention program in addition to the usual medications for heart failure will result in improved symptoms of heart failure and control of the metabolic syndrome
This study will be the first research study to look at the use of diet and exercise in treating heart failure patients who are overweight obese with the metabolic syndrome The study will last 6 months From this study we hope to learn whether diet and exercise is helpful in treating heart failure patients who are overweight Specifically the study will look at the short term effects on cardiac risk factors blood pressure cholesterol blood sugar heart failure symptoms and exercise capacity
People who are obese commonly have other diseases such as high blood pressure high cholesterol and diabetes that increase the risk of developing heart disease It is this group of diseases that is referred to as The Metabolic Syndrome People with the metabolic syndrome also have increased levels of inflammation and clotting proteins in their blood stream Current treatment of the metabolic syndrome involves using medications for cholesterol blood pressure and diabetes Diet and exercise are also commonly recommended
Lifestyle intervention programs are programs that help people lose weight by changing their eating habits and exercise activity routines Weight loss and exercise have been shown to lower the risk of developing diabetes and improve diabetes control improve cholesterol abnormalities and lower blood pressure These programs have not previously included heart failure patients however
We hypothesize that using a lifestyle intervention program in addition to the usual medications for heart failure will result in improved symptoms of heart failure and control of the metabolic syndrome
This study will be the first research study to look at the use of diet and exercise in treating heart failure patients who are overweight obese with the metabolic syndrome The study will last 6 months From this study we hope to learn whether diet and exercise is helpful in treating heart failure patients who are overweight Specifically the study will look at the short term effects on cardiac risk factors blood pressure cholesterol blood sugar heart failure symptoms and exercise capacity
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| K12RR017665 | NIH | None | httpsreporternihgovquickSearchK12RR017665 |