Ignite Creation Date:
2024-05-06 @ 11:13 AM
Last Modification Date:
2024-10-26 @ 12:42 PM
Study NCT ID:
NCT03466762
Status:
COMPLETED
Last Update Posted:
2020-01-09
First Post:
2018-03-01
Brief Title:
Resilience and Quality of Life Among Cancer Survivors
Sponsor:
Aga Khan University
Organization:
Aga Khan University
Study Overview
Official Title:
Resilience and Quality of Life of Head Neck Cancer and Brain Tumor Survivors in Pakistan
Status:
COMPLETED
Status Verified Date:
2020-01
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The main aim of this study is to evaluate the impact of head neck cancer and brain tumors on lives of patients in Pakistan To the best of the investigators knowledge this will be the first in-depth study to evaluate resilience and quality of life QoL among this group of patients These patients encounter challenges as they battle to maintain optimistic outlook towards life Resilience and QoL among them changes over time and may be modifiable towards increased well-being Resilience and QoL are critical components during diagnosis treatment survivorship and at the end of life Hence these are important traits for promoting positive psychological well-being Through this study the investigators will be able to identify problems faced by such patients in our setting the investigators will be able to plan appropriate interventions to improve a persons resiliency and quality of life reduce depression and anxiety and increase their satisfaction with life This study is also aimed to inform healthcare providers and researchers regarding protective or risk characteristics for coping with cancer Practices and resilience interventions may improve well-being and adherence to care guidelines
The objectives of our study are
Primary Objectives
To determine resilience and quality of life scores after treatment separately for head neck cancer and Brain tumor patients in Pakistan
To evaluate important factors associated with resilience and quality of life after treatment separately for head neck cancer and Brain tumor patients in Pakistan
Secondary Objective
To examine the relationship between resilience and quality of life after treatment separately for head neck cancer and Brain tumor patients in Pakistan
It will be an analytical cross sectional study design The study will be conducted at the Aga Khan University Hospital Karachi Study participants will be men and women greater than 18 years with brain tumors or head neck cancer fulfilling the eligibility criteria Approximately 250 patients will be recruiting with brain tumors and 250 with head neck cancer Validated tools will be used to measure resilience and QoL
The objectives of our study are
Primary Objectives
To determine resilience and quality of life scores after treatment separately for head neck cancer and Brain tumor patients in Pakistan
To evaluate important factors associated with resilience and quality of life after treatment separately for head neck cancer and Brain tumor patients in Pakistan
Secondary Objective
To examine the relationship between resilience and quality of life after treatment separately for head neck cancer and Brain tumor patients in Pakistan
It will be an analytical cross sectional study design The study will be conducted at the Aga Khan University Hospital Karachi Study participants will be men and women greater than 18 years with brain tumors or head neck cancer fulfilling the eligibility criteria Approximately 250 patients will be recruiting with brain tumors and 250 with head neck cancer Validated tools will be used to measure resilience and QoL
Detailed Description:
Background In 2012 around 141 million new cases of cancer were diagnosed worldwide and another 82 million died from cancer It is estimated that by 2030 these figures could increase to an alarming 264 million new cases and 17 million cancer-related deaths Nearly 56 of the new cancer cases and 64 of the cancer-related deaths occur in low and middle income countries LMICs where there is a lack of universally available affordable and sustainable health care Head and neck cancers are among the most common cancers worldwide with nearly 600000 new cases and 300000 deaths occurring globally every year Brain tumors are responsible for approximately 2 of all cancer deaths The overall incidence of brain tumors is 4-5100000 population per year Cancers diagnosis considerably affects patients emotional and psychological status The cancer survivors encounter various challenges as they battle to maintain an optimistic outlook towards life Resilience enables individuals to thrive in the face of adversity and it is believed that resilience plays an important role in a cancer survivors life to cope with their illness to overcome depression and improve their Health- related quality of life HR-QoL HR-QoL and its assessment have become increasingly important in health care especially in the field of chronic diseases recently HR-QoL generally refers to patients perceptions of the effects of disease on life It has two fundamental premises first a multi-dimensional concept incorporating physical psychological social and emotional functional domains Second is subjective and must be self-reported according to the patients own experiences Conventionally the endpoints of medical care for cancer patients had focused on survival rate local control rate or complication rate However assessments have lacked knowledge and understanding of the patients mental and emotional wellbeing Recently resilience in the course of cancer treatment has been given immense attention Several studies from different parts of the world on cancer survivors suggest that resilience is a protective factor for distress A study reported resilience was likely to mediate the adverse relationship between cancer symptoms distress and QoL for cancer survivors indicating resilience might play an essential role in protecting against adverse effects of cancer symptoms on QoL It is identified that resilience as an important changeable path can improve hope and QoL Therefore it is important that before initiating treatment patients should be referred to a mental health professional for psychologicalpsychiatric evaluation Resilience and QoL is a critical component during diagnosis treatment survivorship and at the end of life Hence these are important traits for promoting positive psycho-social well-being Resilience and QoL changes over time and may be modifiable towards increased well-being To the best of the investigators knowledge this will be the first in-depth study to evaluate resilience and quality of life among head neck cancer and brain tumor patients in Pakistan Moreover through this study the investigators will be able to identify problems faced by such patients in their setting enabling the investigators in the future to design interventions to improve resilience and QoL
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None