Ignite Creation Date:
2024-05-06 @ 11:08 AM
Last Modification Date:
2024-10-26 @ 12:41 PM
Study NCT ID:
NCT03449706
Status:
RECRUITING
Last Update Posted:
2023-12-07
First Post:
2018-02-22
Brief Title:
Accurate Staging of Immuno-virological Dynamics During Acute HIV Infection
Sponsor:
University Hospital Ghent
Organization:
University Hospital Ghent
Study Overview
Official Title:
Accurate Staging of Immuno-virological Dynamics During Acute HIV Infection
Status:
RECRUITING
Status Verified Date:
2023-11
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
ACS
Brief Summary:
In this prospective longitudinal study we aim to assess how immunologic and viral aspects of the human immunodeficiency virus HIV viral reservoir established during early HIV infection and responsible for viral rebound at treatment interruption evolve in individuals who start combination anti-retroviral therapy cART during acute seroconversion
Recently infected patients will be selected based on Fiebig staging for an in depth sampling protocol at different timepoints during a 2 year follow up period Colonbiopsies lymphnode resection lumbar puncture leucapheresis and repeated peripheral venous blood-draws will be performed Immunological virological and genome expression analysis will be performed on the gathered samples
Recently infected patients will be selected based on Fiebig staging for an in depth sampling protocol at different timepoints during a 2 year follow up period Colonbiopsies lymphnode resection lumbar puncture leucapheresis and repeated peripheral venous blood-draws will be performed Immunological virological and genome expression analysis will be performed on the gathered samples
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None