Ignite Creation Date:
2024-05-06 @ 11:06 AM
Last Modification Date:
2024-10-26 @ 12:40 PM
Study NCT ID:
NCT03436914
Status:
COMPLETED
Last Update Posted:
2020-01-02
First Post:
2018-02-12
Brief Title:
Treatment Response of Maintenance Dose of Proton Pump Inhibitor in Patients With Nonerosive Gatroesophageal Reflux Disease
Sponsor:
Yonsei University
Organization:
Yonsei University
Study Overview
Official Title:
Treatment Response of Maintenance Dose of Proton Pump Inhibitor in Patients With Nonerosive Gatroesophageal Reflux Disease
Status:
COMPLETED
Status Verified Date:
2019-12
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
For ERDerosive reflux disease which pathogenesis is mainly the acid reflux mechanism primary treatment is therefore PPI However NERDnon-erosive reflux disease is much more complex than ERD and there are more factors causing the typical symptoms As a result there is no consensus for the treatment of NERD besides using PPI similar to GERDgastroesophageal reflux diseas This study intent to evaluate the effect of PPIEsomezol on NERD patients and analyze the improvement of symptoms and the factors related to the result
Detailed Description:
1 Among GERD patients EGDesophagogastroduodenoscopy must be done before 6 months and must prove there is no erosive lesion 2 During EGD esophagus mucosa histology will be taken for evaluation 3 For NERD patients Esomezol is given once a day before breakfast meal for whole 8 weeks 4 PAGI-SYM and HAD-K is evaluated and score just before the administration of PPI 4weeks after and 8weeks after the study initiation
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None