Ignite Creation Date:
2024-05-05 @ 4:41 PM
Last Modification Date:
2024-10-26 @ 9:23 AM
Study NCT ID:
NCT00296686
Status:
TERMINATED
Last Update Posted:
2012-04-27
First Post:
2006-02-23
Brief Title:
Sequential Tranylcypromine TC TC Dextroamphetamine and TC Triiodothyronine for Refractory Depression
Sponsor:
New York State Psychiatric Institute
Organization:
New York State Psychiatric Institute
Study Overview
Official Title:
A Pilot Study of Treatment for Refractory Depression With Sequential Trials of Tranylcypromine Tranylcypromine Plus Dextroamphetamine Tranylcypromine Plus Triiodothyronine
Status:
TERMINATED
Status Verified Date:
2012-04
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Study is no longer funded
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
This pilot study will assess the efficacy of several sequential pharmacological treatments for patients with Refractory Depression
Detailed Description:
This pilot study will recruit 40 patients with Major Depression and a history of at least two failed prior adequate somatic treatments In addition to usual physical work-up all patients will have extensive thyroid testing and then will receive standard dose Tranylcypromine ie max 60 mgd Non-remitters will have dose increased to max 120 mgd if tolerated Non-remitters to high dose Tranylcypromine will then have Dextroamphetamine added with frequent blood pressure monitoring to max 40 mgd Non-remitters will have Triiodothyronine added to the Tranylcypromine
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| NCT00296686 | OTHER_GRANT | There is no grantor or funder | None |