Ignite Creation Date:
2024-05-05 @ 11:07 AM
Last Modification Date:
2024-10-26 @ 9:04 AM
Study NCT ID:
NCT00005265
Status:
COMPLETED
Last Update Posted:
2016-05-13
First Post:
2000-05-25
Brief Title:
Natural History of Coronary Heart Disease
Sponsor:
National Heart Lung and Blood Institute NHLBI
Organization:
National Heart Lung and Blood Institute NHLBI
Study Overview
Official Title:
None
Status:
COMPLETED
Status Verified Date:
2001-11
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
To examine the natural history of mortality due to coronary heart disease in post-myocardial infarction patients from the Beta-Blocker Heart Attack Trial BHAT and the Aspirin Myocardial Infarction Study AMIS
Detailed Description:
BACKGROUND
In January 1990 the National Heart Lung and Blood Institute issued a Program Announcement establishing a Small Grants Program to provide limited support to extend analyses of research data generated by clinical trials population research and demonstration and education studies This study used data collected in two completed clinical trials the BHAT and AMIS
DESIGN NARRATIVE
Study endpoints included all-cause mortality cause-specific mortality such as sudden death recurrent and non-fatal myocardial infarction and incident congestive heart failure Univariate and multivariate analyses of baseline data variables from BHAT were conducted to determine which were predictive of study endpoints Baseline variables included sociodemograhic characteristics medical history medication use physical examination finds and electrocardiographic characteristics Baseline characteristics found to be predictive of study endpoints in the BHAT placebo group were examined in the AMIS placebo group Long- and short-term prognoses for patients suffering a transmural myocardial infarction were compared for those suffering a subendocardial infarction
The study completion date listed in this record was obtained from the End Date entered in the Protocol Registration and Results System PRS record
In January 1990 the National Heart Lung and Blood Institute issued a Program Announcement establishing a Small Grants Program to provide limited support to extend analyses of research data generated by clinical trials population research and demonstration and education studies This study used data collected in two completed clinical trials the BHAT and AMIS
DESIGN NARRATIVE
Study endpoints included all-cause mortality cause-specific mortality such as sudden death recurrent and non-fatal myocardial infarction and incident congestive heart failure Univariate and multivariate analyses of baseline data variables from BHAT were conducted to determine which were predictive of study endpoints Baseline variables included sociodemograhic characteristics medical history medication use physical examination finds and electrocardiographic characteristics Baseline characteristics found to be predictive of study endpoints in the BHAT placebo group were examined in the AMIS placebo group Long- and short-term prognoses for patients suffering a transmural myocardial infarction were compared for those suffering a subendocardial infarction
The study completion date listed in this record was obtained from the End Date entered in the Protocol Registration and Results System PRS record
Study Oversight
Has Oversight DMC:
Is a FDA Regulated Drug?:
Is a FDA Regulated Device?:
Is an Unapproved Device?:
Is a PPSD?:
Is a US Export?:
Is an FDA AA801 Violation?:
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| R03HL045495 | NIH | None | httpsreporternihgovquickSearchR03HL045495 |