Ignite Creation Date:
2024-05-05 @ 4:39 PM
Last Modification Date:
2024-10-26 @ 9:22 AM
Study NCT ID:
NCT00289588
Status:
COMPLETED
Last Update Posted:
2006-02-16
First Post:
2006-02-09
Brief Title:
An Attempt to Reduce Community-Acquired Methicillin-Resistant Staphylococcus Aureus MRSA Infection in Soldiers
Sponsor:
Brooke Army Medical Center
Organization:
Brooke Army Medical Center
Study Overview
Official Title:
An Attempt to Reduce Community-Acquired Methicillin-Resistant Staphylococcus Aureus Infection in Soldiers a Controlled Trial
Status:
COMPLETED
Status Verified Date:
2005-12
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The main purpose of this study is to determine if applying mupirocin into soldiers noses who are colonized with methicillin-resistant Staphylococcus aureus MRSA will reduce infections in them and their cohort of fellow soldiers
Detailed Description:
Community-acquired MRSA infections are increasingly common in the community and in particular among certain groups of which soldiers are one Many researchers and clinicians have postulated that one method to prevent infections is to selectively eradicate CA-MRSA in those who are colonized with the pathogen The two main purposes of the study are to determine if selective CA-MRSA eradication in subjects reduces infections in the CA-MRSA colonized individual and to determine if selective CA-MRSA eradication in subjects reduces infections in the study cohort Other information concerning CA-MRSA includes prevalence risk factors and virulence data The population will be soldiers enrolled in the combat medic training class at Ft Sam Houston We will enroll approximately 3000 soldiers over a two year period After informed written consent we will culture their anterior nares nares and administer questionnaires at the beginning and at the end of the study following them prospectively for infections The follow-up period will be 16 weeks For those with CA-MRSA in their nares they will be randomized by cohort to receive either 5 days of mupirocin or placebo
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None