Ignite Creation Date:
2024-05-06 @ 10:47 AM
Last Modification Date:
2024-10-26 @ 12:35 PM
Study NCT ID:
NCT03356938
Status:
COMPLETED
Last Update Posted:
2021-02-21
First Post:
2017-11-15
Brief Title:
The Role of the Circadian System in Neurological Sleep-wake Disorders
Sponsor:
Esther Werth
Organization:
University of Zurich
Study Overview
Official Title:
The Role of the Circadian System in Neurological Sleep-wake Disorders Assessment of Circadian and Homeostatic Sleep-wake Regulation and Vigilance With a Poly-nap Protocol
Status:
COMPLETED
Status Verified Date:
2021-02
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
PNP
Brief Summary:
The aim of this study is to investigate the role of the circadian system in patients with neurologic sleep-wake disorders Therefore overnight sleep will be distributed over 30 hours into repetitive sleep-wake cycles poly-nap protocol so that sleep episodes occur at different circadian phases Vigilance attention risk behavior as well as sleep onset latency will be observed
Ambulatory accelerometer recordings gain more and more attention in the diagnostic work-up of sleep disorders as they allow to also include the everyday rest-activity rhythm before examinations in the sleep laboratory Advances of novel devices should improve the detection of rest and activity and therefore the estimation of sleep and wake especially in patients with neurologic sleep-wake disorders exhibiting fragmented sleep Two types of actimeters will be applied throughout our study protocol to explore better classification of sleep and wake phases and patterns of the rest-activity rhythm
This study is designed as an observational case-controlled study targeting the disorders of narcolepsy type 1 and idiopathic hypersomnia and including interventional procedures in the healthy control group sleep deprivation sleep restriction in a counter-balanced design
Ambulatory accelerometer recordings gain more and more attention in the diagnostic work-up of sleep disorders as they allow to also include the everyday rest-activity rhythm before examinations in the sleep laboratory Advances of novel devices should improve the detection of rest and activity and therefore the estimation of sleep and wake especially in patients with neurologic sleep-wake disorders exhibiting fragmented sleep Two types of actimeters will be applied throughout our study protocol to explore better classification of sleep and wake phases and patterns of the rest-activity rhythm
This study is designed as an observational case-controlled study targeting the disorders of narcolepsy type 1 and idiopathic hypersomnia and including interventional procedures in the healthy control group sleep deprivation sleep restriction in a counter-balanced design
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None