Ignite Creation Date:
2024-05-06 @ 10:39 AM
Last Modification Date:
2024-10-26 @ 12:33 PM
Study NCT ID:
NCT03312413
Status:
UNKNOWN
Last Update Posted:
2017-10-17
First Post:
2017-09-04
Brief Title:
Efficacy of Dexmedetomidine for Cough Suppression in Patients Undergoing Thyroid Surgery
Sponsor:
Min Su
Organization:
First Affiliated Hospital of Chongqing Medical University
Study Overview
Official Title:
Efficacy of Dexmedetomidine for Cough Suppression During Anesthetic Emergence in Patients Undergoing Thyroid Surgery A Randomized Double Blinded Controlled Trial
Status:
UNKNOWN
Status Verified Date:
2017-10
Last Known Status:
RECRUITING
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
EDCSTS
Brief Summary:
Maintenance of a remifentanil infusion during anesthetic emergence has been reported to decrease the incidence of coughing and thereby help to ensure a smooth emergence It may however cause respiratory depression and possibly delay emergence The purpose of this study was to investigate the effect of different dose of dexmedetomidine infusion on cough suppression during emergence from general anesthesia in patients undergoing thyroid surgery
American Society of Anesthesiologists physical status I-II adults undergoing elective thyroidectomy under general anesthesia are recruited and randomly allocated to receive dexmedetomidine iv infusion of 02μgkg-1h-1 Group D1 n 100 05μgkg-1h-1 Group D2 n 100 07μgkg-1h-1 Group D3 n 100 or saline Group C n 100 Primary outcome is the incidence of coughing during emergence Second outcomes include severity of coughing which is assessed using a four-point scale Ramsay score Bruggrmann comfort scale score VAS pain score are recorded The respiratory rate RR heart rate HR and mean arterial pressure are also recorded
American Society of Anesthesiologists physical status I-II adults undergoing elective thyroidectomy under general anesthesia are recruited and randomly allocated to receive dexmedetomidine iv infusion of 02μgkg-1h-1 Group D1 n 100 05μgkg-1h-1 Group D2 n 100 07μgkg-1h-1 Group D3 n 100 or saline Group C n 100 Primary outcome is the incidence of coughing during emergence Second outcomes include severity of coughing which is assessed using a four-point scale Ramsay score Bruggrmann comfort scale score VAS pain score are recorded The respiratory rate RR heart rate HR and mean arterial pressure are also recorded
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
False
Is an FDA AA801 Violation?:
None