Ignite Creation Date:
2024-05-05 @ 11:07 AM
Last Modification Date:
2024-10-26 @ 9:04 AM
Study NCT ID:
NCT00004638
Status:
COMPLETED
Last Update Posted:
2005-06-24
First Post:
2000-02-23
Brief Title:
Immunologic Aspects of the Pathogenesis of Chronic Sinusitis in Children
Sponsor:
National Center for Research Resources NCRR
Organization:
National Center for Research Resources NCRR
Study Overview
Official Title:
None
Status:
COMPLETED
Status Verified Date:
2001-11
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Chronic sinusitis is a common pediatric disease it ranks among the top five infectious diseases of the upper respiratory tract Its treatment is limited and may be due largely in part to a lack of understanding of its cause The investigators have preliminary data to support the notion that pediatric chronic sinusitis is a distinct disease different from acute sinusitis and adult chronic sinusitis We are proposing to perform pathogenesis studies in children with chronic sinusitis Specifically we wish to elucidate the microbiologic features and immunologic factors involved in the formation of this disease The study plan calls for microbiologic bacterial viral and fungal and immunologic inflammatory mediators and leukocyte populations data to be evaluated through a maxillary sinus washing and mucosal biopsies Four populations will be studied and they are 10 children with chronic sinusitis 5 children with acute sinusitis positive control 5 children without sinusitis negative control and 5 adults with chronic sinusitis positive secondary control
Detailed Description:
None
Study Oversight
Has Oversight DMC:
Is a FDA Regulated Drug?:
Is a FDA Regulated Device?:
Is an Unapproved Device?:
Is a PPSD?:
Is a US Export?:
Is an FDA AA801 Violation?:
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| M01RR000069 | NIH | None | httpsreporternihgovquickSearchM01RR000069 |