Ignite Creation Date:
2024-05-06 @ 10:38 AM
Last Modification Date:
2024-10-26 @ 12:33 PM
Study NCT ID:
NCT03314038
Status:
UNKNOWN
Last Update Posted:
2021-02-01
First Post:
2017-10-15
Brief Title:
Syndrome Patterns for Chronic Atrophic Gastritis Malignant Transformation
Sponsor:
Beijing University of Chinese Medicine
Organization:
Beijing University of Chinese Medicine
Study Overview
Official Title:
Validating Features of Traditional Chinese Syndrome Patterns for Chronic Atrophic Gastritis Malignant Transformation A Cross-sectional Study
Status:
UNKNOWN
Status Verified Date:
2021-01
Last Known Status:
RECRUITING
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Chronic atrophic gastritis CAG is acknowledged as the precancerous stage of gastric cancer GC The present study aims to explore Traditional Chinese Medicine TCM syndrome features in different stages of CAG malignant transformation respectively The proposed study is a cross-sectional study based participant survey conducted in 4 hospitals in Beijing China After obtaining informed consent a total of 2000 study patients will be recruited on-site in hospitals
Detailed Description:
CAG is acknowledged as the precancerous stage GC Active treatment of CAG is vital in arresting malignant transformation Traditional Chinese medicine TCM has been widely used in treating CAG and preventing GC in China To date few study has been conducted to assess the syndrome features of different stages of CAG malignant transformation combining TCM indicators
The present study aims to explore TCM syndrome features in different stages of CAG malignant transformation The proposed study is a registry study based participant survey conducted in 4 hospitals in Beijing China After obtaining informed consent a total of 2000 eligible study patients will berecruited on-site in hospitals
Comparative analysis of prevalence of presenting TCM features is conducted using frequency analysis and chi-squared tests and expressed with composition ratios Exploratory factor analysiscorrespondence analysis association rule analysis hierarchical clustering analysis and complex system entropy clustering analysis will be performed respectively for validating features of syndrome in different stages of CAG malignant transformation
Previous reports on TCM syndrome features for CAG exist but no studies have been undertaken base on large-sampled study design and detailed analysis in different stages of CAG malignant transformation respectively
The outcome of our study has the potential to clerify core TCM pathogenesis of CAG facilitate early intervention and promote optimization of treatment strategies of CAG malignant transformation by TCM
The present study aims to explore TCM syndrome features in different stages of CAG malignant transformation The proposed study is a registry study based participant survey conducted in 4 hospitals in Beijing China After obtaining informed consent a total of 2000 eligible study patients will berecruited on-site in hospitals
Comparative analysis of prevalence of presenting TCM features is conducted using frequency analysis and chi-squared tests and expressed with composition ratios Exploratory factor analysiscorrespondence analysis association rule analysis hierarchical clustering analysis and complex system entropy clustering analysis will be performed respectively for validating features of syndrome in different stages of CAG malignant transformation
Previous reports on TCM syndrome features for CAG exist but no studies have been undertaken base on large-sampled study design and detailed analysis in different stages of CAG malignant transformation respectively
The outcome of our study has the potential to clerify core TCM pathogenesis of CAG facilitate early intervention and promote optimization of treatment strategies of CAG malignant transformation by TCM
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None