Ignite Creation Date:
2024-05-06 @ 10:31 AM
Last Modification Date:
2024-10-26 @ 12:30 PM
Study NCT ID:
NCT03270540
Status:
COMPLETED
Last Update Posted:
2018-11-26
First Post:
2017-08-29
Brief Title:
Abdominal Ultrasonography in Urinary Tract Infection - When and Why
Sponsor:
Medical University of Warsaw
Organization:
Medical University of Warsaw
Study Overview
Official Title:
Abdominal Ultrasonography in Urinary Tract Infection - When and Why
Status:
COMPLETED
Status Verified Date:
2018-11
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Urinary tract infection UTI in a child may be the first symptom of congenital anomaly of the kidneys and the urinary tract CAKUT Thus imaging diagnostics are warranted in children with first episode of UTI
Abdominal ultrasonography USG is the first line imaging modality in evaluating children with UTI Abnormalities suggesting CAKUT found on USG are an indication for further more invasive tests The timing of USG in UTI depends on the clinical situation It always should be performed urgently when serious acute complications of UTI are suspected However appropriate timing of USG in children responding well to therapy is a matter of debate According to animal studies E coli produces toxin which dilates the urinary tract This may result in misleading picture on USG in acute phase of infection Guidelines on UTI management in children differ in respect to recommended USG timing
The purpose of the study is to investigate how UTI does affect USG results in children and when its effect subsides
Methods 150 children up to 3 years of age with the first episode of UTI will be included in our study Three USG examinations will be performed by single radiologist in every child
1 in the first day of treatment
2 two weeks after treatment initiation
3 four weeks after treatment initiation Age gender etiologic factor C-reactive protein concentration and white blood cells count will be included in statistical analysis
The study is aimed to help clinicians interpret USG findings during UTI and make reasonable plans for further imaging diagnostics in children with UTI
Abdominal ultrasonography USG is the first line imaging modality in evaluating children with UTI Abnormalities suggesting CAKUT found on USG are an indication for further more invasive tests The timing of USG in UTI depends on the clinical situation It always should be performed urgently when serious acute complications of UTI are suspected However appropriate timing of USG in children responding well to therapy is a matter of debate According to animal studies E coli produces toxin which dilates the urinary tract This may result in misleading picture on USG in acute phase of infection Guidelines on UTI management in children differ in respect to recommended USG timing
The purpose of the study is to investigate how UTI does affect USG results in children and when its effect subsides
Methods 150 children up to 3 years of age with the first episode of UTI will be included in our study Three USG examinations will be performed by single radiologist in every child
1 in the first day of treatment
2 two weeks after treatment initiation
3 four weeks after treatment initiation Age gender etiologic factor C-reactive protein concentration and white blood cells count will be included in statistical analysis
The study is aimed to help clinicians interpret USG findings during UTI and make reasonable plans for further imaging diagnostics in children with UTI
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None