Ignite Creation Date:
2024-05-05 @ 4:37 PM
Last Modification Date:
2024-10-26 @ 9:22 AM
Study NCT ID:
NCT00273143
Status:
COMPLETED
Last Update Posted:
2011-05-24
First Post:
2006-01-06
Brief Title:
A Trial to Study How the Body Fights Off Cytomegalovirus CMV in Hematopoietic Transplant Recipients
Sponsor:
Mayo Clinic
Organization:
Mayo Clinic
Study Overview
Official Title:
Kinetics of Cytomegalovirus CMV Replication and CMV-specific Immune Reconstitution After Hematopoietic Stem Cell Transplantation
Status:
COMPLETED
Status Verified Date:
2011-05
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
This study is being done to determine how the body fights off a common virus known as Cytomegalovirus CMV CMV is a virus that commonly infects humans and causes disease in patients with compromised immune function such as those who receive organ and tissue transplant By knowing how the human body responds to the infection researchers will be able to develop better methods on how to prevent this infection
Detailed Description:
This study is looking at the CMV virus in Hematopoietic stem cell donors and recipients In the donor population the study is looking at the participants blood to see if they contain cells that are active against the virus Information about the donor will be obtained through an interview and through review of medical records A blood sample will be drawn at the time of the donors evaluation which will take place in conjunction with the regular blood tests that are ordered Participants of the study who are donors will only be involved in the study at the time of blood collection
Participants who will be receiving hematopoietic stem cell transplantation will have data collected through an interview and review of medical records Participants will have blood drawn prior to transplant weekly for 12 weeks and then monthly for three months following transplant In addition if CMV disease develops during this period of time blood will be drawn till the participant is cured for the disease All blood draws for thes study will take place in conjunction with the regular routine blood work Participants will be in the study for one year after transplant
Participants who will be receiving hematopoietic stem cell transplantation will have data collected through an interview and review of medical records Participants will have blood drawn prior to transplant weekly for 12 weeks and then monthly for three months following transplant In addition if CMV disease develops during this period of time blood will be drawn till the participant is cured for the disease All blood draws for thes study will take place in conjunction with the regular routine blood work Participants will be in the study for one year after transplant
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None