Ignite Creation Date:
2024-05-06 @ 10:30 AM
Last Modification Date:
2024-10-26 @ 12:31 PM
Study NCT ID:
NCT03272646
Status:
COMPLETED
Last Update Posted:
2017-09-05
First Post:
2017-09-01
Brief Title:
Prognostic Performance of the Naples Prognostic Score
Sponsor:
University of Campania Luigi Vanvitelli
Organization:
University of Campania Luigi Vanvitelli
Study Overview
Official Title:
The Naples Prognostic Score in Gastric Cancer Patients Undergoing Surgery
Status:
COMPLETED
Status Verified Date:
2017-09
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
NPS
Brief Summary:
To investigate the prognostic performance of the Naples Prognostic Score in gastric cancer patients undergoing surgery
Detailed Description:
The outcome of oncological patients is related not only to the tumor status but also to the host Particularly the patients immune and nutritional status have been recently associated with short- and long-term outcome in gastric and other cancers In addition there is growing evidence that systemic inflammation plays a crucial role in the carcinogenesis and progression of gastric cancer The neutrophil to lymphocyte ratio NLR and more recently the lymphocyte to monocyte ratio LMR have been shown to be independently correlated with prognosis in patients with gastric cancer who underwent surgery and preoperative albumin and cholesterol levels seem to be adequate mirrors of the nutritional status of the host
The investigators have already demonstrated that a new scoring system which they called Naples prognostic score NPS based on a composite score of albumin and cholesterol concentrations along with NLR and LMR is a simple tool strongly associated with long-term outcome in patients undergoing surgery for colorectal cancer
The aim of this study is to assess the correlation between the NPS and clinicopathological characteristics postoperative complication rate and long-term outcome in patients undergoing surgery for gastric cancer Furthermore the new prognostic scoring system will be compared with previously developed ones and the current TNM staging system to evaluate its performance
All patients who underwent surgery for proven gastric adenocarcinoma at the Division of Surgical Oncology of the Gastrointestinal Tract of the University of Campania Naples Italy from January 2000 to December 2015 will be enrolled in the present study
The investigators have already demonstrated that a new scoring system which they called Naples prognostic score NPS based on a composite score of albumin and cholesterol concentrations along with NLR and LMR is a simple tool strongly associated with long-term outcome in patients undergoing surgery for colorectal cancer
The aim of this study is to assess the correlation between the NPS and clinicopathological characteristics postoperative complication rate and long-term outcome in patients undergoing surgery for gastric cancer Furthermore the new prognostic scoring system will be compared with previously developed ones and the current TNM staging system to evaluate its performance
All patients who underwent surgery for proven gastric adenocarcinoma at the Division of Surgical Oncology of the Gastrointestinal Tract of the University of Campania Naples Italy from January 2000 to December 2015 will be enrolled in the present study
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None