Ignite Creation Date:
2024-05-06 @ 10:25 AM
Last Modification Date:
2024-10-26 @ 12:29 PM
Study NCT ID:
NCT03251326
Status:
TERMINATED
Last Update Posted:
2022-07-15
First Post:
2017-08-14
Brief Title:
Nabilone in Cannabis Users With PTSD
Sponsor:
New York State Psychiatric Institute
Organization:
New York State Psychiatric Institute
Study Overview
Official Title:
Effects of Nabilone on Trauma Related Cue Reactivity in Cannabis Users With PTSD
Status:
TERMINATED
Status Verified Date:
2022-06
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Recruitment difficulties
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Despite the prevalence of cannabis use among the PTSD population and self-reports that it is used to help cope with PTSD symptoms the direct effects of cannabis on PTSD symptomology are unknown The purpose of this placebo-controlled within-subject study is to assess the effects of smoked cannabis and orally administered nabilone a synthetic analog of THC the primary psychoactive component of cannabis on multiple dimensions of PTSD symptomatology in cannabis smokers with PTSD
Detailed Description:
This study will compare the effects of smoked cannabis and nabilone on attentional bias toward trauma- related stimuli subjective and emotional processing to a range of trauma-and non-trauma-related images and physiological reactivity to these stimuli in individuals with CUD and PTSD Importantly this study will also probe the abuse related potential of nabilone compared to smoked cannabis in this population a critical aspect in determining the potential feasibility for its use clinically to treat CUD in PTSD populations The effects of nabilone will be compared to propranolol as a positive control
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
True
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| U54DA037842 | NIH | None | httpsreporternihgovquickSearchU54DA037842 |