Ignite Creation Date:
2024-05-05 @ 4:36 PM
Last Modification Date:
2024-10-26 @ 9:22 AM
Study NCT ID:
NCT00279227
Status:
UNKNOWN
Last Update Posted:
2006-08-15
First Post:
2006-01-17
Brief Title:
Role of Epicardial Adipose Tissue in Coronary Artery Disease
Sponsor:
Hamilton Health Sciences Corporation
Organization:
McMaster University
Study Overview
Official Title:
Role of Epicardial Adipose Tissue in Coronary Artery Disease
Status:
UNKNOWN
Status Verified Date:
2006-01
Last Known Status:
RECRUITING
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
We sight to evaluate whether patients with coronary artery disease CAD have more epicardial fat than patients without CAD which would suggest that epicardial fat may be more than an innocent bystander and be actively involved in the disease process Its role as a modulator of vascular response and myocardial function could potentially lead to new areas of cardiac research We also sight to evaluate whether epicardial fat from patients with CAD releases more adipokines than subcutaneous fat from these patients which could prompt studies into the differential regulation of adipokine secretion in this tissue Thus for eg the use of thiazolidinediones glitazones statins ARBs or other compounds that can specifically modulate adipokine secretion could be explored to determine their benefit in ameliorating the effects attributable to increased epicardial fat
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None