Ignite Creation Date:
2024-05-06 @ 10:23 AM
Last Modification Date:
2024-10-26 @ 12:29 PM
Study NCT ID:
NCT03246295
Status:
UNKNOWN
Last Update Posted:
2017-08-11
First Post:
2017-07-23
Brief Title:
Identification of Gestational Diabetes Mellitus Related Urinary Biomarkers Along Pregnancy From Early Pregnancy to Postpartum by Using Proteomics and Metabolomics Analysis
Sponsor:
Peking Union Medical College Hospital
Organization:
Peking Union Medical College Hospital
Study Overview
Official Title:
Identification of Gestational Diabetes Mellitus Related Urinary Biomarkers Along Pregnancy From Early Pregnancy to Postpartum by Using Proteomics and Metabolomics Analysis
Status:
UNKNOWN
Status Verified Date:
2017-08
Last Known Status:
ACTIVE_NOT_RECRUITING
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Gestational diabetes mellitus GDM has many adverse effects on pregnant women and fetuses At present no prediction marker for GDM in early pregnancy is accepted There is still a lack of recognized early predictors This study was designed to identity valuable biomarkers for GDMThis was a prospective observed cohort study 140 pregnant women were recruited in early pregnancy and followed up to 6 weeks postpartum Glucose challenge test and 75g oral glucose tolerance test were performed after 24 weeks of pregnancy and GDM was diagnosed according to the latest ADA standard Urinary samples were collected in the first 12 weeks second 2428 weeks and third 32weeks trimester of pregnancy Urinary proteomics and metabolomics were analyzed by ultra-performance liquid chromatography tandem mass spectrometry 15 cases of GDM women and 50 cases of control women were used for longitudinal analysis 15 cases of GDM women and 15 cases of age matched control women were used for difference analysis
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None