Ignite Creation Date:
2024-05-06 @ 10:20 AM
Last Modification Date:
2024-10-26 @ 12:28 PM
Study NCT ID:
NCT03220542
Status:
UNKNOWN
Last Update Posted:
2019-06-04
First Post:
2017-07-09
Brief Title:
The Effect of Broccoli Sprout Extract and Probiotics for Eradication of Helicobacter Pylori
Sponsor:
Kyunghee University Medical Center
Organization:
Kyunghee University Medical Center
Study Overview
Official Title:
The Effect of Broccoli Sprout Extract and Probiotics on Proton Pump Inhibitor-based Triple Therapy for Eradication of Helicobacter Pylori a Prospective Randomized Trial
Status:
UNKNOWN
Status Verified Date:
2019-05
Last Known Status:
ACTIVE_NOT_RECRUITING
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
In Korea the first-line therapy to treat Helicobacter pylori Hp consists of a proton pump inhibitor PPI and two antibiotics for one week But eradication has become less successful due to low compliance and high resistance to the antibiotics Therefore it is necessary to develop new treatment strategies that increase the eradication rate and reduce adverse effects In vitro study we previously reported that a broccoli sprout extract containing sulforaphane may prevent lipid peroxidation in the gastric mucosa and play a cytoprotective role in Hp-induced gastritis Also several studies suggested that probiotics could be effective for improving Hp eradication rate or reducing adverse events But their effect for eradication of Hp is not yet conclusive The aims of this prospective study is to investigate the efficacy of a broccoli sprout extract containing sulforaphane and probiotics for eradication of Hp compared with standard triple therapy
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None