Ignite Creation Date:
2024-05-06 @ 10:17 AM
Last Modification Date:
2024-10-26 @ 12:27 PM
Study NCT ID:
NCT03217942
Status:
COMPLETED
Last Update Posted:
2018-01-11
First Post:
2017-07-10
Brief Title:
Spread of Muscle Hyperalgesia and Pain in a Low Dose NGF-induced Pain Model
Sponsor:
Aalborg University
Organization:
Aalborg University
Study Overview
Official Title:
Spread of Muscle Hyperalgesia and Pain in a Low Dose NGF-induced Pain Model
Status:
COMPLETED
Status Verified Date:
2018-01
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The purpose of this study is to investigate and determine the time course and distribution on muscle hyperalgesia and muscle pain in a repeated low dose NGF model It is hypothesized that low dosages im injections of NGF are able to induce mechanical hyperalgesia and muscle soreness in a same manner effect of duration as for dosages previously used in NGF studies Furthermore it is also speculated if several injections of low dose NGF into the muscle combined are able to course immediate pain sensation and spreading of muscle hypersensitivity
Detailed Description:
Effects of pain responses symptom development and pattern time course and distribution following 5 im low dose injections of NGF injected into the tibialis anterior muscle will be compared to a high dose im injection of NGF injected into the contralateral side in healthy pain-free subjects
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
False
Is an FDA AA801 Violation?:
None