Ignite Creation Date:
2024-05-06 @ 10:17 AM
Last Modification Date:
2024-10-26 @ 12:28 PM
Study NCT ID:
NCT03218813
Status:
COMPLETED
Last Update Posted:
2019-08-14
First Post:
2017-07-12
Brief Title:
A Pharmacist-Led Hospital-Based Intervention to Support Medication Adherence Following Acute Coronary Syndrome
Sponsor:
Kings College London
Organization:
Kings College London
Study Overview
Official Title:
A Pharmacist-Led Hospital-Based Intervention to Support Medication Adherence Following Acute Coronary Syndrome An Intervention Cohort Study
Status:
COMPLETED
Status Verified Date:
2018-08
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Background Medication adherence following acute coronary syndrome ACS is often sub-optimal and is associated with poor clinical outcomes Patients beliefs about medications have been shown to predict poor adherence and may be targetable for intervention Findings novel ways to improve adherence is an important area of research with widespread clinical implications Pharmacists may currently be underutilised in promoting and monitoring medication-taking behaviour There have been few effective interventions led by pharmacists to support medication adherence in patients with ACS
Objectives This study follows on from a feasibility and acceptability study recently conducted NCT02967588 The primary objective is to pilot a pharmacist-led hospital-based intervention to support medication adherence following an ACS
Methods This study will adopt a non-randomised intervention cohort design ie controlled before-and-after CBA study Patients admitted to hospital with an ACS will be recruited for this study Patients must be prescribed medicines for secondary prevention The study will be delivered by hospital pharmacists over two sessions and will target both intentional Session 1 and unintentional Session 2 adherence barriers Session 1 will involve eliciting and challenging patients erroneous beliefs about medications Session 2 will involve formulating specific action plans to encourage medication-taking habit formation
Outcome Outcome data will be collected at two time points - 6 week and 12 week follow up The primary outcome of this proposed study will be treatment beliefs measured using the Beliefs about Medicines Questionnaire-Specific BMQ-S Horne Weinman Hankin 1999 Our secondary outcome will be self-reported medication adherence measured using the Medication Adherence Report Scale MARS-5 Horne Weinman 2002 Depression medicines-related self-efficacy and satisfaction with medicines information provision will also be measured
Study timeline Control cohort before group eligible patients will receive treatment as usual TAU and will complete all outcome measures ie treatment beliefs medication adherence Pharmacists will then be trained to deliver the intervention Intervention cohort after group eligible patients will receive the pharmacist-led intervention and will complete all outcome measures
Objectives This study follows on from a feasibility and acceptability study recently conducted NCT02967588 The primary objective is to pilot a pharmacist-led hospital-based intervention to support medication adherence following an ACS
Methods This study will adopt a non-randomised intervention cohort design ie controlled before-and-after CBA study Patients admitted to hospital with an ACS will be recruited for this study Patients must be prescribed medicines for secondary prevention The study will be delivered by hospital pharmacists over two sessions and will target both intentional Session 1 and unintentional Session 2 adherence barriers Session 1 will involve eliciting and challenging patients erroneous beliefs about medications Session 2 will involve formulating specific action plans to encourage medication-taking habit formation
Outcome Outcome data will be collected at two time points - 6 week and 12 week follow up The primary outcome of this proposed study will be treatment beliefs measured using the Beliefs about Medicines Questionnaire-Specific BMQ-S Horne Weinman Hankin 1999 Our secondary outcome will be self-reported medication adherence measured using the Medication Adherence Report Scale MARS-5 Horne Weinman 2002 Depression medicines-related self-efficacy and satisfaction with medicines information provision will also be measured
Study timeline Control cohort before group eligible patients will receive treatment as usual TAU and will complete all outcome measures ie treatment beliefs medication adherence Pharmacists will then be trained to deliver the intervention Intervention cohort after group eligible patients will receive the pharmacist-led intervention and will complete all outcome measures
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None