Ignite Creation Date:
2024-05-05 @ 4:34 PM
Last Modification Date:
2024-10-26 @ 9:21 AM
Study NCT ID:
NCT00263302
Status:
SUSPENDED
Last Update Posted:
2008-07-04
First Post:
2005-12-07
Brief Title:
Diuretic Efficacy of Dexamethasone in Heart Failure
Sponsor:
Hebei Medical University
Organization:
Hebei Medical University
Study Overview
Official Title:
Diuretic Efficacy of Dexamethasone in Congestive Heart Failure Patients
Status:
SUSPENDED
Status Verified Date:
2005-01
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The purpose of this study is to determine whether glucocorticoids have potent diuretic effects in patients with congestive heart failure
Detailed Description:
Glucocorticoids are known to have pronounced physiological effects in the kidney Conventional teaching dictates that it should be used with caution in patients with congestive heart failure due to its fluid and sodium retention effects Surprisingly despite the widespread prevalence of this belief within the medical community there are few data to support it In fact several small animal studies have documented its striking diuretic effects due to increased renal plasma flow and glomerular filtration rate without changes in the glomerular filtration fraction We design this study to determine whether glucocorticoids have a potent diuretic effect in patients with heart failure
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None