Ignite Creation Date:
2024-05-05 @ 4:34 PM
Last Modification Date:
2024-10-26 @ 9:21 AM
Study NCT ID:
NCT00260104
Status:
UNKNOWN
Last Update Posted:
2008-05-26
First Post:
2005-11-29
Brief Title:
Risk Factors of Individuals With Coronary Artery Disease
Sponsor:
Nanjing Medical University
Organization:
Nanjing Medical University
Study Overview
Official Title:
None
Status:
UNKNOWN
Status Verified Date:
2008-05
Last Known Status:
RECRUITING
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
It would be useful to study coronary arteriovenous difference of various markers in patients who are undergoing coronary angiography for suspected coronary artery disease Environmental and genetic factors may play a role in the progression of coronary artery disease The goal of this project is to establish a series of cross-sectional case-control studies to evaluate risk factors of coronary artery disease in China
Detailed Description:
This study is designed to investigate the epidemiologic genetic laboratory and clinical characterization of individuals with coronary artery disease The study group will consist of consecutive patients who are undergoing coronary angiography for suspected coronary artery disease The diagnosis of coronary artery disease will be confirmed by coronary angiography performed with the Judkins technique using a quantitative coronary angiographic system Coronary artery disease will be considered to be present if there is a diameter stenosis of at least 50 in at least one of the three major epicardial coronary arteries The number of diseased vessels will be determined and a classification of 1- 2- and 3-vessel disease will be used Coronary artery segments will be defined according to the Coronary Artery Surgery Study classification Blood samples from vein and coronary artery will be collected We will study coronary arteriovenous difference of various markers Urinary samples will be obtained the day of coronary angiography We will explore the environmental including family history life style diet physical activity neuropsychological functioningplasma levels of oxidative stress factors angiogenic factors and inflammatory markers etc and genetic including oxidative stress factors and inflammatory factors etc risk factors We will study the association between various environmental risk factors with the clinical characterization and correlation between the genetic polymorphisms and the presence of coronary artery disease
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None