Ignite Creation Date:
2024-05-06 @ 10:08 AM
Last Modification Date:
2024-10-26 @ 12:25 PM
Study NCT ID:
NCT03175705
Status:
UNKNOWN
Last Update Posted:
2018-01-18
First Post:
2017-05-24
Brief Title:
Adoptive Transfer of Specific HCC Antigens CD8 T Cells for Treating Patients With RelapsedAdvanced HCC
Sponsor:
Beijing YouAn Hospital
Organization:
Beijing YouAn Hospital
Study Overview
Official Title:
A Study of Specific HCC Antigens CD8 T Cells Therapy for Treating Patients With RelapsedAdvanced Hepatocellular Carcinoma HCC
Status:
UNKNOWN
Status Verified Date:
2018-01
Last Known Status:
RECRUITING
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
This study enrolls patients who have relapsedadvanced hepatocellular carcinoma HCC BCLC stage C The HCC tumor relapsed or metastasized through the body after standard treatment or the patients cannot receive standard treatment under current conditions This research study uses specific HCC antigens CD8 T cells a new experimental treatment
The purpose of this study is to evaluate the safety and tolerance as well as the potential clinical efficacy of an adoptive transfer of CD8 T cells sorted with human leukocyte antigen HLA-peptide multimers and specific for Glypican GPC-3 New York Esophageal Squamous-1 NY-ESO-1 alpha-fetoprotein AFP antigens and cultured in vitro to patients suffering from relapsedadvanced hepatocellular carcinoma HCC
The purpose of this study is to evaluate the safety and tolerance as well as the potential clinical efficacy of an adoptive transfer of CD8 T cells sorted with human leukocyte antigen HLA-peptide multimers and specific for Glypican GPC-3 New York Esophageal Squamous-1 NY-ESO-1 alpha-fetoprotein AFP antigens and cultured in vitro to patients suffering from relapsedadvanced hepatocellular carcinoma HCC
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None