Ignite Creation Date:
2024-05-06 @ 10:07 AM
Last Modification Date:
2024-10-26 @ 12:25 PM
Study NCT ID:
NCT03170453
Status:
ACTIVE_NOT_RECRUITING
Last Update Posted:
2024-06-04
First Post:
2017-02-27
Brief Title:
Confirmatory Efficacy Trial of Cognitive Enhancement Therapy for Adult Autism Spectrum Disorder
Sponsor:
University of Pittsburgh
Organization:
University of Pittsburgh
Study Overview
Official Title:
Cognitive Enhancement Therapy for Adult Autism Spectrum Disorder
Status:
ACTIVE_NOT_RECRUITING
Status Verified Date:
2024-06
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
PerspectivesII
Brief Summary:
This study will investigate and confirm the efficacy of two psychological treatments for adults with autism spectrum disorder Cognitive Enhancement Therapy CET is a cognitive remediation intervention that aims to help adults with problems in thinking planning and socialization Enriched Supportive Therapy EST is an individual supportive therapy that aims to help adults learn about their condition manage their emotions and stress improve their social skills and cope with everyday problems
Detailed Description:
Autism spectrum disorder ASD is characterized by marked impairments in social and non-social cognitive ability that persist well into adulthood and contribute to significant functional disability The treatment of ASD has focused almost exclusively on children and few empirically supported interventions are available to address the core cognitive and functional challenges individuals with ASD face as they transition to adulthood This study will investigate and confirm the efficacy of two psychological treatments for adults with autism spectrum disorder Cognitive Enhancement Therapy CET is a cognitive remediation intervention that aims to help adults with problems in thinking planning and socialization Enriched Supportive Therapy EST is an individual supportive therapy that aims to help adults learn about their condition manage their emotions and stress improve their social skills and cope with everyday problems
Participation in this study will last 30 months Potential participants must be able to attend weekly treatment sessions in Pittsburgh PA
The study design is a 30-month 25 years randomized-controlled confirmatory efficacy trial where eligible participants will be randomized to the CET or EST study treatments Participants will be treated with the study interventions for 18 months and then followed for 12 additional months to assess the lasting impact of the study interventions All participants will complete cognitive clinical and neuroimaging magnetic resonance imaging assessments prior to starting the study treatments and then at specified intervals thereafter to evaluate the impact of the study treatments on cognition adaptive function and the brain
Participation in this study will last 30 months Potential participants must be able to attend weekly treatment sessions in Pittsburgh PA
The study design is a 30-month 25 years randomized-controlled confirmatory efficacy trial where eligible participants will be randomized to the CET or EST study treatments Participants will be treated with the study interventions for 18 months and then followed for 12 additional months to assess the lasting impact of the study interventions All participants will complete cognitive clinical and neuroimaging magnetic resonance imaging assessments prior to starting the study treatments and then at specified intervals thereafter to evaluate the impact of the study treatments on cognition adaptive function and the brain
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| R01MH106450 | NIH | None | httpsreporternihgovquickSearchR01MH106450 |