Ignite Creation Date:
2024-05-06 @ 10:07 AM
Last Modification Date:
2024-10-26 @ 12:24 PM
Study NCT ID:
NCT03164798
Status:
COMPLETED
Last Update Posted:
2020-03-18
First Post:
2017-05-21
Brief Title:
Serum BDNF Role as a Biomarker for Stroke Rehabilitation
Sponsor:
Samsung Medical Center
Organization:
Samsung Medical Center
Study Overview
Official Title:
Serum BDNF Role as a Biomarker for Stroke Rehabilitation
Status:
COMPLETED
Status Verified Date:
2020-03
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
BDNF
Brief Summary:
This study aims to develop the quantitative biomarker to establish the individualized strategy in stroke rehabilitation Brain-derived neurotrophic factor BDNF acts on certain neurons of the central nervous system CNS helping to support the survival of existing neurons and encourage the growth and differentiation of new neurons and synapses BDNF in CNS can be assessed by analysing serum BDNF The final objective of this study is to demonstrate a role of biomarker of BDNF in stroke rehabilitation to establish the individualized strategy
Detailed Description:
Serum BDNF proBDNF and MMP-9 in all participants will be measured before and after the comprehensive inpatient rehabilitation during subacute stroke phase At 3 months after stroke onset serum BDNF proBDNF and MMP-9 will also be measured
In addition motor impairment with Fugl-Meyer assessement will be assessed at same time points with serum analysis
We will compare potential serum biomarkers with motor impairment in stroke patients
In addition motor impairment with Fugl-Meyer assessement will be assessed at same time points with serum analysis
We will compare potential serum biomarkers with motor impairment in stroke patients
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None