Ignite Creation Date:
2024-05-06 @ 10:03 AM
Last Modification Date:
2024-10-26 @ 12:24 PM
Study NCT ID:
NCT03157258
Status:
COMPLETED
Last Update Posted:
2023-03-01
First Post:
2017-05-09
Brief Title:
Social Network Intervention to Engage Community PLH to Engage in HIV Medical Care
Sponsor:
Medical College of Wisconsin
Organization:
Medical College of Wisconsin
Study Overview
Official Title:
Social Network Intervention to Engage Community PLH to Engage in HIV Medical Care
Status:
COMPLETED
Status Verified Date:
2023-02
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
People living with HIV infection PLH are clustered in friendship groups with other HIV persons and an intervention delivered to all members of PLH social networks allows HIV people who are friends in day-to-day life to provide one another with support for entering remaining and adhering to HIV medical care Moreover an intervention delivered to groups attended by HIV persons who are friends increases HIV medical care engagement and decreases problem drinking more than individual counseling probably because the network intervention harnessed mutual peer social support among friends who share the same HIV status face similar coping issues and interact together in day-to-day life The planned research will be conducted in two phases in St Petersburg Russia
Detailed Description:
Phase I of the planned research will be the conduct of in-depth interviews with 30 HIV persons not in medical care or not adherent to anti-retroviral therapy ART regimens including men and women representing diverse exposure risks drug use men who have sex with men and heterosexual transmission Interviews will elicit information on ways in which HIV-positive friends can support one another in HIV care entry retention and adherence types of support from PLH friends that would best support treatment engagement and how peer supports can lessen the negative effects of substance use on care engagement
Phase 2 will recruit 48 out-of-care or ART nonadherent HIV individuals from community settings in St Petersburg Russia These individuals who are referred to as network seeds will invite their HIV friends who will in turn invite their own HIV friends into the study creating a sample of 48 networks expected n288 6 membersnetwork x 48 networks Following baseline assessment of care engagement ART adherence treatment attitudes psychosocial distress substance use and CD4 and viral load 24 networks n144 participants will be randomized to an intervention condition and 24 networks n144 to the comparison condition All members of each intervention condition network will together attend a 4-session intervention to strengthen attitudes intentions and skills for entering remaining and adhering to HIV medical care Because participants will attend sessions with other individuals who are their own friends in day-to-day life the intervention will build and increase mutual social support within each network for HIV care and adherence Peer champions identified in each intervention network will attend 3 additional sessions in which they are guided to reinforce and help to sustain friends medical care engagement Intervention outcomes will be determined by baseline to 6- and 12-month followup change on primary measures of participant attendance at HIV medical care visits adherence to ART regimens and viral load as well as secondary measures of alcohol use drug use sexual risk behavior treatment attitudes and psychosocial distress
Phase 2 will recruit 48 out-of-care or ART nonadherent HIV individuals from community settings in St Petersburg Russia These individuals who are referred to as network seeds will invite their HIV friends who will in turn invite their own HIV friends into the study creating a sample of 48 networks expected n288 6 membersnetwork x 48 networks Following baseline assessment of care engagement ART adherence treatment attitudes psychosocial distress substance use and CD4 and viral load 24 networks n144 participants will be randomized to an intervention condition and 24 networks n144 to the comparison condition All members of each intervention condition network will together attend a 4-session intervention to strengthen attitudes intentions and skills for entering remaining and adhering to HIV medical care Because participants will attend sessions with other individuals who are their own friends in day-to-day life the intervention will build and increase mutual social support within each network for HIV care and adherence Peer champions identified in each intervention network will attend 3 additional sessions in which they are guided to reinforce and help to sustain friends medical care engagement Intervention outcomes will be determined by baseline to 6- and 12-month followup change on primary measures of participant attendance at HIV medical care visits adherence to ART regimens and viral load as well as secondary measures of alcohol use drug use sexual risk behavior treatment attitudes and psychosocial distress
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None