Ignite Creation Date:
2025-12-24 @ 4:16 PM
Ignite Modification Date:
2025-12-25 @ 2:24 PM
Study NCT ID:
NCT05212766
Status:
UNKNOWN
Last Update Posted:
2023-10-10
First Post:
2022-01-24
Is NOT Gene Therapy:
True
Has Adverse Events:
False
Brief Title:
Role of the Oral Microbiome & Mucosal Immunity in COVID-19 Disease
Sponsor:
King's College London
Organization:
Study Overview
Official Title:
Role of the Oral Microbiome & Mucosal Immunity in COVID-19 Disease: Diagnostic/Prognostic Utility in South Asian Populations
Status:
UNKNOWN
Status Verified Date:
2023-10
Last Known Status:
RECRUITING
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
MIMSA
Brief Summary:
Determining whether in the mouth there are differences between the participant groups in the nature and activity of mucosal innate immunity, in immune responses to SARS-COV2 antigens, or in the oral microbiome
Detailed Description:
Cross sectional with longitudinal component
* Stimulated whole mouth fluid (SWMF) and blood samples from South Asian and non-Asian populations
* Controls, and COVID-19 patients in both populations.
* Oral disease questionnaire and clinical examination
* Separation of SWMF into pellet for DNA extraction for microbiomics and supernatant for cell phenotype analysis, cytokines and antibodies to SARS-CoV2 antigens
* Stimulated whole mouth fluid (SWMF) and blood samples from South Asian and non-Asian populations
* Controls, and COVID-19 patients in both populations.
* Oral disease questionnaire and clinical examination
* Separation of SWMF into pellet for DNA extraction for microbiomics and supernatant for cell phenotype analysis, cytokines and antibodies to SARS-CoV2 antigens
Study Oversight
Has Oversight DMC:
False
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?: