Ignite Creation Date:
2024-05-06 @ 9:57 AM
Last Modification Date:
2024-10-26 @ 12:22 PM
Study NCT ID:
NCT03114176
Status:
COMPLETED
Last Update Posted:
2017-04-14
First Post:
2017-04-04
Brief Title:
Effects of Ketogenic Diet in Divers Breathing Enriched Air Nitrox
Sponsor:
University of Padova
Organization:
University of Padova
Study Overview
Official Title:
Effects of Exercise and Dietary Inatke on Muscle Metabolism and Inflammatory Status Modulated by Oxygen Free Radicals and Cytokines in Humans
Status:
COMPLETED
Status Verified Date:
2017-04
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Overweight divers face a challenging activity such as immersions starting from a higher levels of circulating cytokines and oxidative stress Ketogenic Diet KD is described as effective in weight loss in countering inflammation and oxidative stress and used in the control of drug-refractory seizures
The aim of our pilot study was to evaluate if a ketosis state induced by a specific dietary regime may have a protective effect on oxidative stress damages and inflammatory status that accompanies both overweight and diving activities
Blood and urine samples from six overweight divers were obtained a before CTRL and after a dive breathing Enriched Air Nitrox and performing light underwater exercise NTRX b after a dive same conditions performed after 7 days of KD K-NTRX We measured urinary 8-isoprostane and 8-OH-2-deoxyguanosine evaluating lipids peroxidation and DNA oxidative damages Plasmatic IL-1beta IL-6 and TNF-alpha levels were measured to investigate the inflammatory status
The aim of our pilot study was to evaluate if a ketosis state induced by a specific dietary regime may have a protective effect on oxidative stress damages and inflammatory status that accompanies both overweight and diving activities
Blood and urine samples from six overweight divers were obtained a before CTRL and after a dive breathing Enriched Air Nitrox and performing light underwater exercise NTRX b after a dive same conditions performed after 7 days of KD K-NTRX We measured urinary 8-isoprostane and 8-OH-2-deoxyguanosine evaluating lipids peroxidation and DNA oxidative damages Plasmatic IL-1beta IL-6 and TNF-alpha levels were measured to investigate the inflammatory status
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
False
Is an FDA AA801 Violation?:
None