Ignite Creation Date:
2024-05-05 @ 12:09 PM
Last Modification Date:
2024-10-26 @ 9:20 AM
Study NCT ID:
NCT00251615
Status:
COMPLETED
Last Update Posted:
2012-08-06
First Post:
2005-11-08
Brief Title:
Calcium Channel Splice Variant Expression in Cardiovascular Disease and Aging
Sponsor:
National Institute on Aging NIA
Organization:
National Institutes of Health Clinical Center CC
Study Overview
Official Title:
Calcium Channel Splice Variant Expression in Cardiovascular Disease and Aging
Status:
COMPLETED
Status Verified Date:
2012-08
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The purpose of this study is to learn what changes in blood vessel contraction may occur as a result of a disease of the vessel that requires surgery The study will examine the calcium channels present in the vessels being operated on and the genes that may alter blood vessel function Possible variation in these genes may change the kind of calcium channels present in blood vessels
Detailed Description:
The goal of this study is to learn more about how blood vessels function and the mechanism that causes them to contract The study will investigate the natural history of diseased blood vessel tissue and the calcium channels in the muscle part of the blood vessel The study will also examine how genetics influences cardiovascular disease and its causes and treatments
Patients scheduled for vascular surgery will be approached to participate in this study During surgery tissue fragments of diseased and marginal tissue will be obtained A blood sample will be obtained at either the time of surgery or consent and genomic DNA will be extracted
Patients scheduled for vascular surgery will be approached to participate in this study During surgery tissue fragments of diseased and marginal tissue will be obtained A blood sample will be obtained at either the time of surgery or consent and genomic DNA will be extracted
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None