Ignite Creation Date:
2024-05-06 @ 9:49 AM
Last Modification Date:
2024-10-26 @ 12:20 PM
Study NCT ID:
NCT03081559
Status:
COMPLETED
Last Update Posted:
2020-11-16
First Post:
2017-03-06
Brief Title:
Improving Engagement in HIV Care for High-risk Women
Sponsor:
University of California San Francisco
Organization:
University of California San Francisco
Study Overview
Official Title:
Improving Engagement in HIV Care for High-risk Women
Status:
COMPLETED
Status Verified Date:
2020-11
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Transgender women assigned male at birth but who do not identify as male are disproportionately impacted by HIV and have culturally unique barriers and facilitators to engagement in HIV care Transgender women living with HIV TWH are less likely than others to take antiretroviral therapy ART and those who initiate ART have lower rates of ART adherence lower self-efficacy for integrating ART into daily routines and report fewer positive interactions with health care providers than non-transgender adults As a result TWH have an almost three-fold higher viral load than non-transgender adults in San Francisco in Los Angeles TWH are less likely to be virally suppressed than any other behavioral risk group In formative work the investigators have identified culturally-specific and modifiable barriers to HIV treatment engagement among TWH including prioritization of transition-related health care ie hormone therapy at the expense of HIV treatment avoidance of HIV care settings due to past negative health care experiences misinformation about ART including potential drug interactions with hormones intensified HIV stigma low levels of social support and poor coping skills There are both individual and public health consequences to poor engagement in care among TWH stemming from high transmission risk factors including substance abuse high numbers of sex partners engagement in sex work and high rates of mental illness These findings strongly suggest that TWH face unique challenges to engaging in and adhering to HIV treatment and that the public health consequences for poor engagement in this population are of grave concern Interventions to mitigate these barriers to engagement in care are critical in efforts to alter the pattern of HIV-related disparities that lead to disproportionately poor health outcomes for this highly vulnerable and marginalized population The investigators are conducting a randomized controlled trial of a theory-driven population-specific piloted intervention to improve engagement in care for TWH Grounded in the investigators Models of Gender Affirmation and Health Care Empowerment the proposed research is the first to systematically intervene on complex barriers to optimal engagement in HIV care for TWH The investigators have developed and piloted the Healthy Divas intervention to optimize engagement in HIV care for TWH at elevated risk for treatment failure and consequential morbidity mortality and transmission of HIV
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None