Ignite Creation Date:
2024-05-06 @ 9:46 AM
Last Modification Date:
2024-10-26 @ 12:19 PM
Study NCT ID:
NCT03064711
Status:
COMPLETED
Last Update Posted:
2017-02-27
First Post:
2017-02-22
Brief Title:
Activity and Fatigue of the Respiratory Muscles and Pulmonary Characteristics in Post-Polio Patients
Sponsor:
Hadassah Medical Organization
Organization:
Hadassah Medical Organization
Study Overview
Official Title:
Comparison of Activity and Fatigue of the Respiratory Muscles and Pulmonary Characteristics Between Post-Polio Patients and Healthy Controls A Pilot Study
Status:
COMPLETED
Status Verified Date:
2017-02
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Background Early diagnosis of respiratory impairment in Post-Polio PPS patients may delay respiratory decline and future need of invasive respiratory aids
Objectives To compare pulmonary function measures maximal respiratory pressure and activity levels and fatigue of respiratory muscles between patients with PPS and healthy controls
Design Cross-sectional study Setting Hadassah physical medicine and rehabilitation department Jerusalem Patients Patients with PPS N12 6 males age 621116 years able to walk for 6 minutes without human assistance age-matched healthy subjects N12 4 males age 62265 years
Intervention None Measurements A body plethysmograph was used to quantify forced expiratory volume in the first second of a forced expiratory maneuver vital capacity slow vital capacity Residual Volume RV Total Lung Capacity TLC and Thoracic Gas Volume TGV Also RV to TLC ratio is calculated A manometer was used to measure Maximal Inspiratory Pressure MIP and Maximal Expiratory Pressure MEP A spirometer was used to measure Maximal Voluntary Ventilation MVV Surface electromyography sEMG recorded diaphragmatic muscle activity during rest and while performing MVV
Objectives To compare pulmonary function measures maximal respiratory pressure and activity levels and fatigue of respiratory muscles between patients with PPS and healthy controls
Design Cross-sectional study Setting Hadassah physical medicine and rehabilitation department Jerusalem Patients Patients with PPS N12 6 males age 621116 years able to walk for 6 minutes without human assistance age-matched healthy subjects N12 4 males age 62265 years
Intervention None Measurements A body plethysmograph was used to quantify forced expiratory volume in the first second of a forced expiratory maneuver vital capacity slow vital capacity Residual Volume RV Total Lung Capacity TLC and Thoracic Gas Volume TGV Also RV to TLC ratio is calculated A manometer was used to measure Maximal Inspiratory Pressure MIP and Maximal Expiratory Pressure MEP A spirometer was used to measure Maximal Voluntary Ventilation MVV Surface electromyography sEMG recorded diaphragmatic muscle activity during rest and while performing MVV
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None