Ignite Creation Date:
2025-12-24 @ 4:12 PM
Ignite Modification Date:
2026-01-22 @ 10:56 AM
Study NCT ID:
NCT02359266
Status:
COMPLETED
Last Update Posted:
2015-02-09
First Post:
2015-02-04
Is Gene Therapy:
True
Has Adverse Events:
False
Brief Title:
Vitamin D Improves Depression in Liver Patients
Sponsor:
Universität des Saarlandes
Organization:
Study Overview
Official Title:
Clinical Trial Investigating the Role of Vitamin D in the Treatment of Depression in Patients With Chronic Liver Disease
Status:
COMPLETED
Status Verified Date:
2015-02
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
CLDVitD
Brief Summary:
This study evaluates the efficacy of vitamin D replacement therapy in reducing depressive symptoms in patients with chronic liver disease and vitamin D deficiency. Patients with normal vitamin D levels will be monitored as controls, and they will not receive any intervention.
Detailed Description:
Patients with chronic liver diseases regularly suffer from vitamin D deficiency and depression. A recent meta-analysis reported an inverse correlation between depression and vitamin D levels. Indeed, vitamin D receptor is present and genomic and nongenomic vitamin D receptor-mediated signalling has been described in brain.
This intervention study investigates whether vitamin D therapy ameliorates depressive symptoms in chronic liver disease patients.
The investigators hypothesise that depressive symptoms will improve upon vitamin D replacement therapy.
This intervention study investigates whether vitamin D therapy ameliorates depressive symptoms in chronic liver disease patients.
The investigators hypothesise that depressive symptoms will improve upon vitamin D replacement therapy.
Study Oversight
Has Oversight DMC:
False
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?: