Ignite Creation Date:
2024-05-06 @ 9:43 AM
Last Modification Date:
2024-10-26 @ 12:19 PM
Study NCT ID:
NCT03059966
Status:
COMPLETED
Last Update Posted:
2017-02-23
First Post:
2017-01-19
Brief Title:
Evaluation of the Inflammatory and Healing Profile After Root Coverage With Emdogain
Sponsor:
Rio de Janeiro State University
Organization:
Rio de Janeiro State University
Study Overview
Official Title:
Evaluation of the Inflammatory and Healing Profile After Root Coverage With Emdogain
Status:
COMPLETED
Status Verified Date:
2017-02
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The purpose of this study was the evaluation of inflammatory and healing profile after root coverage using of Enamel Matrix Derivative 16 volunteers were selected and submitted to root coverage surgery with subepithelial connective tissue graft with and without enamel matrix derivative The patient screening was based in the following inclusion criteria bilateral recessions in maxillary anterior homologous teeth with aesthetical complaining ou hypersensitivity non-smokers healthy and no use of any medication that compromises periodontal health or healing The split-mouth randomized model was followed in relation to test and control sites The following clinical parameters were analyzed at baseline and 6-month post-surgery recession height recession width width of keratinized tissue probing depth clinical attachment level and gingival thickness In addition to the surgical analysis evaluations of the following inflammatory markers were performed IL-1β IL -1RA IL-2 IL-4 IL-5 IL-6 IL-7 IL-8 IL-9 IL-10 IL12 IL-13 IL-15 IL-17 EOTAXIN FGF GCSF GMCSF IFN-y IP-10 MCP-1 MIP 1a PDGF-bb MIP 1b RANTES TNF-α e VEGF These evaluations were performed at baseline 7 and 14 days after surgery
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
True
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
False
Is an FDA AA801 Violation?:
None